Ideas

April 24, 2018
Published by admin_auro at April 24, 2018
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A glycolipid way to treat autoimmune diabetes (TIDM): α-Galactosylceramide, a synthetic glycolipid, increases PD-L1 expression, increases Tregs function, promotes immune tolerance, increases pancreatic β-cell proliferation and regeneration, increases insulin secretion, improves insulin sensitivity, increases energy utilization, and reverses TIDM, via up regulation of its target gene, 24/April/2018, 7.50 am

Introduction: What they say A study from the International Center for T1D, Pediatric Clinical Research Center Romeo ed Enrica Invernizzi, “L. Sacco” Department of Biomedical and Clinical […]
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April 22, 2018
Published by admin_auro at April 22, 2018
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Therapeutic insights into “awakening the sleeping/cancer-protecting angels” in mutant p53-expressing human tumors: Dexoycholic acid increases the expression of tumor suppressors genes, such as TA-p73/p63, TPM1, and others, induces regression of p53-mutated human tumors, via down regulation of its target gene, 22/April/2017, 11.29 pm

From Significance of the study to Public health relevance:  Given that: (1) cancer suppressor p53 is mutated in more than 50% of human cancers of different […]
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April 22, 2018
Published by admin_auro at April 22, 2018
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Therapeutic insights into “awakening the sleeping/cancer-protecting angels” in mutant p53-expressing human tumors: Amitriptyline (trade name: Elavil), a medication used to treat major depressive disorder, anxiety disorder, and bipolar disorder, increases the expression of tumor suppressors genes, such as TIMP3, CCM3/KRIT1, TA-p73/p63, TPM1, and others, induces regression of p53-mutated human tumors, via down regulation of its target gene, 22/April/2017, 11.24 pm

From Significance of the study to Public health relevance:  Given that: (1) cancer suppressor p53 is mutated in more than 50% of human cancers of different […]
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April 22, 2018
Published by admin_auro at April 22, 2018
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Molecular therapy for Deafness: A therapeutic mix encompassing Clofibrate, Cholecalciferol, Ajoene and DIM (CCAD) increases the expression of ATG5 (Autophagy-related 5), prevents aggregation of proteins in inclusion bodies, inhibits hair cell degeneration,  improves hearing loss via up regulation of its target genes, 22/April/2018, 11.12 pm

  What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Molecular therapy for Deafness: A therapeutic mix encompassing Clofibrate, Cholecalciferol, Ajoene and DIM (CCAD) increases the […]
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