Ideas

Cardiac rejuvenation therapy: Rotigotine, an antidepressant drug, suppresses tumor suppressor INK4a/p16 expression, promotes cardiac repair, delays cardiac ageing and senescence, and extends life span via up regulation of its target gene, 5/December/2017, 11.43 pm
Cardiac rejuvenation therapy: Rotigotine, an antidepressant drug, suppresses tumor suppressor INK4a/p16 expression, promotes cardiac repair, delays cardiac ageing and senescence, and extends life span via up regulation of its target gene, 5/December/2017, 11.43 pm 960 720 Dr Boomi's Genom-2-Discovery Center

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Cardiac rejuvenation therapy: Rotigotine, an antidepressant drug, suppresses tumor suppressor INK4a/p16 expression, promotes cardiac repair, delays cardiac ageing and…

read more

Antidepressants as Cardioprotective agents: Paroxetine (Trade name: Paxil and Seroxat), an antidepressant, increases Agrin expression, activates Yap and ERK-mediated signaling,  replaces scar tissue with functional cardiomyocytes, and promotes cardiomyocyte regeneration and repair after myocardial infarction, via up regulation of its target gene, 4/December/2017, 11.48 pm
Antidepressants as Cardioprotective agents: Paroxetine (Trade name: Paxil and Seroxat), an antidepressant, increases Agrin expression, activates Yap and ERK-mediated signaling,  replaces scar tissue with functional cardiomyocytes, and promotes cardiomyocyte regeneration and repair after myocardial infarction, via up regulation of its target gene, 4/December/2017, 11.48 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say: A recent study from Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 76100, Israel; Department of Biomedical Engineering, Duke University, Durham, North Carolina 27708,…

read more

Combinatorial therapy for Cardiomyopathy: A therapeutic mix encompassing Paroxetine and Astaxanthin (PA) decreases the expression of Sox6, restores the balance between slow- and fast-twitch myofiber proteins and alleviates Cardiomyopathy via up regulation of its target gene, 4/December/2017,  11.40 pm
Combinatorial therapy for Cardiomyopathy: A therapeutic mix encompassing Paroxetine and Astaxanthin (PA) decreases the expression of Sox6, restores the balance between slow- and fast-twitch myofiber proteins and alleviates Cardiomyopathy via up regulation of its target gene, 4/December/2017,  11.40 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A recent study from the Department of Cardiology, Boston Children’s Hospital, Harvard Medical School, Boston, Massachusetts, USA; and Harvard Stem Cell Institute, Harvard University, Cambridge, Massachusetts, USA shows that “Trbp regulates heart function through microRNA-mediated Sox6 repression.” This…

read more

Activation of the PD-1 pathway for Pain therapy: Eucalyptol, isolated from  Eucalyptus Globulus, Cinnamomum camphora, Bay leaves, and Rosemary, among others,   increases the expression of PD-L1, attenuates acutes and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability via up-regulation of its target gene, 4/November/2017, 11.27 pm
Activation of the PD-1 pathway for Pain therapy: Eucalyptol, isolated from  Eucalyptus Globulus, Cinnamomum camphora, Bay leaves, and Rosemary, among others,   increases the expression of PD-L1, attenuates acutes and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability via up-regulation of its target gene, 4/November/2017, 11.27 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction:What they say: A recent study from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain Science, Fudan University, Shanghai,…

read more

Natural product-derived therapy for attenuating pathogenesis of Myocardial infarction: (–)-Catechin, found abundantly in Camellia Sinensis, decreases GM-CSF (Granulocyte-macrophage colony-stimulating factor) expression, inhibits undue leucocyte activation and invasion, suppresses recruitment of inflammatory cells, inhibits left ventricular rupture, and promotes heart healing via up regulation of its target gene, 4/December/2017, 11.14 pm
Natural product-derived therapy for attenuating pathogenesis of Myocardial infarction: (–)-Catechin, found abundantly in Camellia Sinensis, decreases GM-CSF (Granulocyte-macrophage colony-stimulating factor) expression, inhibits undue leucocyte activation and invasion, suppresses recruitment of inflammatory cells, inhibits left ventricular rupture, and promotes heart healing via up regulation of its target gene, 4/December/2017, 11.14 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say: A recent study from Center for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA; and Center for Systems Biology, Massachusetts General Hospital…

read more

Natural product-based therapy for Deafness: A therapeutic mix encompassing Venlafaxine, Cholecalciferol, Ajoene and DIM (VCAD)  increases the expression of ATG5 (Autophagy-related 5), prevents aggregation of proteins in inclusion bodies, inhibits hair cell degeneration,  improves hearing loss via up regulation of its target genes, 4/December/2017, 11.04 pm
Natural product-based therapy for Deafness: A therapeutic mix encompassing Venlafaxine, Cholecalciferol, Ajoene and DIM (VCAD)  increases the expression of ATG5 (Autophagy-related 5), prevents aggregation of proteins in inclusion bodies, inhibits hair cell degeneration,  improves hearing loss via up regulation of its target genes, 4/December/2017, 11.04 pm 960 720 Dr Boomi's Genom-2-Discovery Center

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Natural product-based therapy for Deafness: a therapeutic mix encompassing Venlafaxine, Cholecalciferol, Ajoene and DIM (VCAD)  increases the expression of ATG5 (Autophagy-related 5),…

read more
Start Typing