Ideas

Lifespan extension therapy:  6-Shogaol, isolated from Zingiber Officinale Roscoe, increases life span via up-regulation of its target gene BubR1, 2/December/2017, 6.27 am
Lifespan extension therapy:  6-Shogaol, isolated from Zingiber Officinale Roscoe, increases life span via up-regulation of its target gene BubR1, 2/December/2017, 6.27 am 960 720 Dr Boomi's Genom-2-Discovery Center

 What they say: Introduction:  A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston,USA; and Department of Pharmacology, School…

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Natural product-based therapy for body weight control, energy homeostasis and TIIDM: Glabridin, an isoflavane isolated from Licorice (Glycyrrhiza glabra),  inhibits DNA methyltransferase 3a (Dnmt3a) expression, increases FGF21 expression, augments insulin sensitivity, increases glucose tolerance, and protects from diet-induced obesity and TIIDM, via up regulation of its target gene, 2/December/2017, 6.14 am
Natural product-based therapy for body weight control, energy homeostasis and TIIDM: Glabridin, an isoflavane isolated from Licorice (Glycyrrhiza glabra),  inhibits DNA methyltransferase 3a (Dnmt3a) expression, increases FGF21 expression, augments insulin sensitivity, increases glucose tolerance, and protects from diet-induced obesity and TIIDM, via up regulation of its target gene, 2/December/2017, 6.14 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from Nutritional Sciences and Toxicology Department, University of California, Berkeley, Berkeley, United States shows that “Dnmt3a is an epigenetic mediator of adipose insulin resistance.”…

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Molecular therapy for Cardiomyopathy: A pharmacological mixture encompassing Cilostazol and Aripiprazole decreases the expression of Sox6, restores the balance between slow- and fast-twitch myofiber proteins and alleviates Cardiomyopathy via up regulation of its target gene, 2/December/2017,  12.07 am
Molecular therapy for Cardiomyopathy: A pharmacological mixture encompassing Cilostazol and Aripiprazole decreases the expression of Sox6, restores the balance between slow- and fast-twitch myofiber proteins and alleviates Cardiomyopathy via up regulation of its target gene, 2/December/2017,  12.07 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say   A study from the Department of Cardiology, Boston Children’s Hospital, Harvard Medical School, Boston, Massachusetts, USA; and Harvard Stem Cell Institute, Harvard University, Cambridge, Massachusetts, USA shows that “Trbp regulates heart function through microRNA-mediated Sox6 repression.” This…

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Regenerative therapy for muscle atrophy: Cilostazol, a phosphodiesterase inhibitor used in the treatment of Peripheral vascular disease, increases the expression of IGF-1, PI3K(p85a) and B-Myb, decreases the expression of tumor suppressors, promotes regeneration of muscle cells, and reverses muscle atrophy via up regulation of its target gene, 1/November/2017, 11.58 pm
Regenerative therapy for muscle atrophy: Cilostazol, a phosphodiesterase inhibitor used in the treatment of Peripheral vascular disease, increases the expression of IGF-1, PI3K(p85a) and B-Myb, decreases the expression of tumor suppressors, promotes regeneration of muscle cells, and reverses muscle atrophy via up regulation of its target gene, 1/November/2017, 11.58 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Cardiac Regeneration and Ageing Lab, School of Life Science, Shanghai University, Shanghai 200444, China shows that “miR-29b contributes to multiple types of…

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Molecular therapy for Stroke: Cilostazol, a phosphodiesterase inhibitor used in the treatment of Perpheral vascular disease, attenuates hippocampal neurons injury, augments regenerative neurogenesis after Ischemic Stroke, and ameliorates stroke damage and neurological deficits via up regulation of its target genes BDNF and NAMPT, 1/December/2017, 6.44 pm
Molecular therapy for Stroke: Cilostazol, a phosphodiesterase inhibitor used in the treatment of Perpheral vascular disease, attenuates hippocampal neurons injury, augments regenerative neurogenesis after Ischemic Stroke, and ameliorates stroke damage and neurological deficits via up regulation of its target genes BDNF and NAMPT, 1/December/2017, 6.44 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A recent study from Research Center for Neurobiology and Department of Neurobiology, Xuzhou Medical College, 209 Tongshan Road, Xuzhou, Jiangsu 221004, PR China; and School of Public…

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Antiviral therapy for HIV virus:  A pharmaceutical mixture encompassing  Cidofovir and Ribavirin (CR) increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production via up regulation of its target gene, 1/December/2017, 5.22 pm
Antiviral therapy for HIV virus:  A pharmaceutical mixture encompassing  Cidofovir and Ribavirin (CR) increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production via up regulation of its target gene, 1/December/2017, 5.22 pm 960 720 Dr Boomi's Genom-2-Discovery Center

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Antiviral therapy for HIV virus:  A pharmaceutical mixture encompassing  Cidofovir and Ribavirin (CR) increases Heme oxygenase 2 (HO-2) expression,…

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