Ideas

Regenerative therapy for regaining the lost cardiomyocytes in Myocardial patients: A pharmaceutical mixture encompassing Aripiprazole and Cilostazol increases the expression of ERBB2/Her2 and promotes dedifferentiation  of cardiomyocytes via down regulation of its target gene, 3/December/2017, 10.40 pm
Regenerative therapy for regaining the lost cardiomyocytes in Myocardial patients: A pharmaceutical mixture encompassing Aripiprazole and Cilostazol increases the expression of ERBB2/Her2 and promotes dedifferentiation  of cardiomyocytes via down regulation of its target gene, 3/December/2017, 10.40 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A recent study from the Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel shows that “ERBB2 triggers mammalian heart regeneration by promoting cardiomyocyte dedifferentiation and proliferation.” This study was published, in the 6 April…

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Molecular therapy for Deafness: A therapeutic mix encompassing Paroxetine, Cholecalciferol, Ajoene and DIM (PCAD)  increases the expression of ATG5 (Autophagy-related 5), prevents aggregation of proteins in inclusion bodies, inhibits hair cell degeneration,  improves hearing loss via up regulation of its target genes, 3/December/2017, 10.26 pm
Molecular therapy for Deafness: A therapeutic mix encompassing Paroxetine, Cholecalciferol, Ajoene and DIM (PCAD)  increases the expression of ATG5 (Autophagy-related 5), prevents aggregation of proteins in inclusion bodies, inhibits hair cell degeneration,  improves hearing loss via up regulation of its target genes, 3/December/2017, 10.26 pm 960 720 Dr Boomi's Genom-2-Discovery Center

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Molecular therapy for Deafness: A therapeutic mix encompassing Paroxetine, Cholecalciferol, Ajoene and DIM (PCAD)  increases the expression of ATG5 (Autophagy-related 5), prevents…

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Natural product-derived therapy for Stroke: Eucalyptol, isolated from Eucalyptus globulus,  Cinnamomum camphora, Bay leaves, and Rosemary, among others, attenuates hippocampal neurons injury, augments regenerative neurogenesis after Ischemic Stroke, and ameliorates stroke damage and neurological deficits via up regulation of its target genes BDNF and NAMPT, 3/December/2017, 10.03 pm
Natural product-derived therapy for Stroke: Eucalyptol, isolated from Eucalyptus globulus,  Cinnamomum camphora, Bay leaves, and Rosemary, among others, attenuates hippocampal neurons injury, augments regenerative neurogenesis after Ischemic Stroke, and ameliorates stroke damage and neurological deficits via up regulation of its target genes BDNF and NAMPT, 3/December/2017, 10.03 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A recent study from Research Center for Neurobiology and Department of Neurobiology, Xuzhou Medical College, 209 Tongshan Road, Xuzhou, Jiangsu 221004, PR China; and School of Public…

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Molecular therapy for Myocardial Infarction: Cilostazol, a phosphodiesterase inhibitor used in the treatment of peripheral vascular disease,  inhibits DNA damage responses, induces telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction via up regulation of PNUTS, 3/December/2017, 9.35 pm
Molecular therapy for Myocardial Infarction: Cilostazol, a phosphodiesterase inhibitor used in the treatment of peripheral vascular disease,  inhibits DNA damage responses, induces telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction via up regulation of PNUTS, 3/December/2017, 9.35 pm 960 720 Dr Boomi's Genom-2-Discovery Center

What they say:  A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published, in the 7 March  2013 issue of Nature,  by Prof Dimmler, Boon, and others. What we…

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Molecular therapy for heart regeneration and repair: A therapeutic mix encompassing Aripiprazole and Cilostazol increases Agrin expression, activates Yap and ERK-mediated signaling,  replaces scar tissue with functional cardiomyocytes, and promotes cardiomyocyte regeneration and repair after myocardial infarction, via up regulation of its target gene, 2/December/2017, 8.39 am
Molecular therapy for heart regeneration and repair: A therapeutic mix encompassing Aripiprazole and Cilostazol increases Agrin expression, activates Yap and ERK-mediated signaling,  replaces scar tissue with functional cardiomyocytes, and promotes cardiomyocyte regeneration and repair after myocardial infarction, via up regulation of its target gene, 2/December/2017, 8.39 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say: A recent study from Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 76100, Israel; Department of Biomedical Engineering, Duke University, Durham, North Carolina 27708,…

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Natural product-based therapy for TIIDM and obesity-associated metabolic deficits: Meranzin hydrate, isolated from Humulus Scandens, increases Lipocalin 2 (LCN2) expression, activates an MC4R-dependent anorexigenic pathway, suppresses appetite and weight gain, increases insulin secretion, improves glucose tolerance, promotes glucose homeostasis, improves obesity-associated metabolic deficits and prevents progression to TIIDM via down regulation of its target gene, 2/December/2017, 7.41 am
Natural product-based therapy for TIIDM and obesity-associated metabolic deficits: Meranzin hydrate, isolated from Humulus Scandens, increases Lipocalin 2 (LCN2) expression, activates an MC4R-dependent anorexigenic pathway, suppresses appetite and weight gain, increases insulin secretion, improves glucose tolerance, promotes glucose homeostasis, improves obesity-associated metabolic deficits and prevents progression to TIIDM via down regulation of its target gene, 2/December/2017, 7.41 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Department of Physiology-Cellular Biophysics, College of Physicians and Surgeons, Columbia University, New York, New York, USA shows that “MC4R-dependent suppression of appetite…

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