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Ideas

November 12, 2017

Natural product-derived therapy for anxiety and depression:  Cucurbitacin, isolated from Watermelon, decreases PHF8 levels, increases the expression of serotonin receptors Htr1a and Htr2a, and promotes resistance to stress-induced -anxiety and -depression via down regulation of its target gene, 13/November/2017, 12.17 am

Introduction: What they say: A study from Department of Molecular Biology, Cancer Center and Center for Regenerative Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA; Department […]
November 12, 2017

Molecular therapy for Non-alcoholic fatty liver disease (NAFLD): Victoza/Saxenda, an anti-hyperglycemic drug, promotes degradation of HMGCR, decreases the levels of triglycerides, free cholesterol, and total cholesterol and prevents the progression of Non-alcoholic fatty liver disease (NAFLD via down regulation of its target gene, 12/November/2017, 11.15 pm

Significance of the study: Given that: (1)  15-30% of Western populations suffer from Non-alcoholic fatty liver disease (NAFLD), while 6-25% of Asian populations suffer from it; (2) 75 to […]
November 12, 2017

Life-extension therapy: Mangiferin, isolated from Mangifera Indica, inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span, 12/November/2017, 11.10 pm

What they say: A study from the Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK shows that “Ribosomal […]
November 11, 2017

Natural product therapy for pulmonary arterial hypertension:Mangiferin, isolated from Mangifera Indica, inhibits the development of pulmonary arterial hypertension via down regulation of  Notch3 and its target gene Hes5, 11/November/2017, 11.59 pm

What they say:  A study from the University of California, La Jolla, California, USA shows that “Notch3 signaling promotes the development of pulmonary arterial hypertension.” This study was published in the 15 November  2009 issue of the journal “Nature Medicine”[the number […]
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