Ideas

February 10, 2018

Molecular therapy for pulmonary arterial hypertension: Fenofibrate inhibits the development of pulmonary arterial hypertension via down regulation of its target gene Notch3, 10/February/2018, 11.23 pm

What they say:  A study from the University of California, La Jolla, California, USA shows that “Notch3 signaling promotes the development of pulmonary arterial hypertension.” This study was published, in the 15 November  2009 issue of the journal “Nature Medicine”[the number […]
February 10, 2018

Molecular therapy for Anti-ageing and Lifespan extension:  Atorvastatin, a medication used in the treatment of cardiovascular disease,  increases CHIP levels, increases monoubiquitylation of insulin receptor (INSR), decreases INSR protein levels and enhances lifespan via down regulation of its target gene, 10/February/2018, 11.15 pm

Introduction: What they say A study from Institute for Cell Biology, University of Bonn, Ulrich-Haberland Str.  Bonn, Germany; and Institute for Genetics and CECAD Research Center, […]
February 10, 2018

Amino acid-based therapy for diabetes (TIDM): Taurine (2-aminoethanesulfonic acid) increases GLP1R and Caveolin-1 (CAV-1) expression, promotes glucose-induced insulin secretion, improves insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM via up regulation of its target gene, 10/February/2017,11.00 am

Introduction: What they say A study from the Comprehensive Diabetes Center and Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of Alabama at Birmingham, […]
February 10, 2018

Activation of the PD-1 pathway for Pain therapy: D-3-Hydroxybutyrate (D3HB) increases the expression of PD-L1, attenuates acutes and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability via up-regulation of its target gene, 10/February/2017, 8.00 pm

Introduction:What they say: A recent study, from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain […]
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