Ideas

Natural product-derived therapy for Myocardial Infarction: Hypaphorine, isolated from Caragana korshinskii Kom, inhibits DNA damage responses, induces telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction via  up-regulation of PNUTS,  25/November/2017, 3.55 pm
Natural product-derived therapy for Myocardial Infarction: Hypaphorine, isolated from Caragana korshinskii Kom, inhibits DNA damage responses, induces telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction via  up-regulation of PNUTS,  25/November/2017, 3.55 pm 960 720 Dr Boomi's Genom-2-Discovery Center

What they say:  A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published, in the 7 March  2013 issue of Nature,  by Prof Dimmler, Boon, and others. What we…

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Molecular therapy for Non-alcoholic fatty liver disease (NAFLD): Lysophosphatidic acid (LPA) promotes degradation of HMGCR, decreases the levels of triglycerides, free cholesterol, and total cholesterol and prevents the progression of Non-alcoholic fatty liver disease (NAFLD via down regulation of its target gene, 25/November/2017, 3.45 pm
Molecular therapy for Non-alcoholic fatty liver disease (NAFLD): Lysophosphatidic acid (LPA) promotes degradation of HMGCR, decreases the levels of triglycerides, free cholesterol, and total cholesterol and prevents the progression of Non-alcoholic fatty liver disease (NAFLD via down regulation of its target gene, 25/November/2017, 3.45 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Significance of the study: Given that: (1)  15-30% of Western populations suffer from Non-alcoholic fatty liver disease (NAFLD), while 6-25% of Asian populations suffer from it; (2) 75 to 100 million people in…

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 Natural product Lifespan extension therapy: Magnolol, found in  Houpu magnolia, increases life span via up-regulation of its target gene BubR1, 24/November/2017, 11.18 pm
 Natural product Lifespan extension therapy: Magnolol, found in  Houpu magnolia, increases life span via up-regulation of its target gene BubR1, 24/November/2017, 11.18 pm 960 720 Dr Boomi's Genom-2-Discovery Center

 What they say: Introduction:  A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston,USA; and Department of Pharmacology, School…

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Natural product-derived therapy for anxiety and depression: Nordihydroguaiaretic acid (NDGA), isolated from Larrea tridentata, decreases PHF8 levels, increases the expression of serotonin receptors Htr1a and Htr2a, and promotes resistance to stress-induced -anxiety and -depression via down regulation of its target gene, 24/November/2017, 10.51 pm
Natural product-derived therapy for anxiety and depression: Nordihydroguaiaretic acid (NDGA), isolated from Larrea tridentata, decreases PHF8 levels, increases the expression of serotonin receptors Htr1a and Htr2a, and promotes resistance to stress-induced -anxiety and -depression via down regulation of its target gene, 24/November/2017, 10.51 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say: A study from Department of Molecular Biology, Cancer Center and Center for Regenerative Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA; Department of Stem Cell and…

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Activation of the PD-1 pathway for Pain therapy:  D-Serine increases the expression of PD-L1, attenuates acutes and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability via up-regulation of its target gene, 24/November/2017, 1.21 pm
Activation of the PD-1 pathway for Pain therapy:  D-Serine increases the expression of PD-L1, attenuates acutes and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability via up-regulation of its target gene, 24/November/2017, 1.21 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction:What they say: A recent study from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain Science, Fudan University, Shanghai,…

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Natural product-derived therapy for Stroke: Safranal, isolated from Saffron, Rooibos and among others, attenuates hippocampal neurons injury, augments regenerative neurogenesis after Ischemic Stroke, and ameliorates stroke damage and neurological deficits via up regulation of its target genes BDNF and NAMPT, 24/November/2017, 8.14 am
Natural product-derived therapy for Stroke: Safranal, isolated from Saffron, Rooibos and among others, attenuates hippocampal neurons injury, augments regenerative neurogenesis after Ischemic Stroke, and ameliorates stroke damage and neurological deficits via up regulation of its target genes BDNF and NAMPT, 24/November/2017, 8.14 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A recent study from Research Center for Neurobiology and Department of Neurobiology, Xuzhou Medical College, 209 Tongshan Road, Xuzhou, Jiangsu 221004, PR China; and School of Public…

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