Ideas

April 22, 2018

Published by admin_auro at April 22, 2018

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Molecular therapy for Deafness: A therapeutic mix encompassing Clofibrate, Cholecalciferol, Ajoene and DIM (CCAD) increases the expression of ATG5 (Autophagy-related 5), prevents aggregation of proteins in inclusion bodies, inhibits hair cell degeneration, improves hearing loss via up regulation of its target genes, 22/April/2018, 11.12 pm

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Molecular therapy for Deafness: A therapeutic mix encompassing Clofibrate, Cholecalciferol, Ajoene and DIM (CCAD) increases the […]

April 22, 2018

Published by admin_auro at April 22, 2018

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Molecular therapy for blood-stage Plasmodium infection: Oleic acid, isolated from olive oil, avocado and others, decreases the expression of CTLA-4, PD-L1 and LAG-3, promotes CD4+ T-cell function, increases secretion of protective antibodies, promotes and clear blood-stage malaria via up regulation of its target gene, 22/April/2018, 11.03 pm

Introduction: What they say A study from the Department of Microbiology and Immunology, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA shows that […]

April 21, 2018

Published by admin_auro at April 21, 2018

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Mechanistic insights into how Brimonidine functions as an anti-glaucoma agent: Brimonidine (trade name: Alphagan and Alphagan-P), used in the treatment of open-angle glaucoma and ocular hypertension, increases Nmnat1 expression, increases NAD+ levels, improves neuronal dysfunction, and protects against glaucoma, via down regulation of its target gene, 21/April/2018, 8.54 am

Introduction: What they say A study from the The Jackson Laboratory, Bar Harbor, ME 04609, USA; Department of Ophthalmology, Tufts University of Medicine, Boston, MA 02111, […]

April 21, 2018

Published by admin_auro at April 21, 2018

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Natural product-derived therapy for cardiomyocyte proliferation and heart regeneration: A pharmaceutical mixture encompassing Panaxynol, Triptolide and Sulforaphane (PTS) decreases tumor suppressor MiR-128 and cyclin-dependent kinase inhibitor p27 expression, increases SUZ12 expression, increases Cyclin E and CDK2 expression, promotes proliferation/re-entry of postnatal/adult cardiomyocytes, attenuates fibrosis, ameliorates cardiac dysfunction, and promotes heart repair in response to myocardial infarction, via up regulation of its target gene, 21/April/2018, 8.10am

Introduction: What they say: A recent study from Department of Pathology and Laboratory Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, 45267, USA; Key Laboratory […]