Ideas

June 17, 2019

Solving a century-old puzzle as to how Sesame oil functions as a pain reliever: Mechanistic insights into how Sesame oil-derived compounds function as pain medications: A pharmaceutical mixture encompassing Sesamin and Sesamol (SAS), derived from Sesame seed or oil, increases the expression of PD-L1, decreases the expression of Cox-2, attenuates acutes and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability, via up-regulation of its target gene, 17/June/2019, 12.58 pm

Solving a century-old puzzle as to how Sesame oil functions as a pain reliever: Mechanistic insights into how Sesame oil-derived compounds function as pain medications: A pharmaceutical mixture encompassing Sesamin and Sesamol (SAS), derived from Sesame seed or oil, increases the expression of PD-L1, decreases the expression of Cox-2, attenuates acutes and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability, via up-regulation of its target gene, 17/June/2019, 12.58 pm https://genomediscovery.org/wp-content/uploads/2019/06/Sesame-oil-attenuates-acute-and-chronic-pain-through-induction-of-PD-L1-and-down-regulation-of-Cox-2.jpg4_.jpg5_.jpg 1280 720 Dr Boomi's Genom-2-Discovery Center Dr Boomi's Genom-2-Discovery Center https://genomediscovery.org/wp-content/uploads/2019/06/Sesame-oil-attenuates-acute-and-chronic-pain-through-induction-of-PD-L1-and-down-regulation-of-Cox-2.jpg4_.jpg5_.jpg June 17, 2019 June 18, 2019

Introduction:What they say: A recent study from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain Science, Fudan University, Shanghai,…

June 17, 2019

Probiotic-based chemotherapy targeting cancer stem cells and immune-inhibitory receptors in advanced metastatic cancers: A pharmaceutical mixture encompassing a pharmacological formulation encompassing Metformin, Navitoclax/ABT-263, & Dasatinib (MND) and probiotic Lactobacillus rhamnosus increases the expression of tumor suppressor genes, such as BIRC5, p12DOC1, p53, and TA-p73/p63, inhibits immune-inhibitory receptors/molecules, targets cancer stem cells, confers protection against chemoresistance and prolongs survival, via up-regulation of its target gene, 17/June/2019, 6.14 am

Probiotic-based chemotherapy targeting cancer stem cells and immune-inhibitory receptors in advanced metastatic cancers: A pharmaceutical mixture encompassing a pharmacological formulation encompassing Metformin, Navitoclax/ABT-263, & Dasatinib (MND) and probiotic Lactobacillus rhamnosus increases the expression of tumor suppressor genes, such as BIRC5, p12DOC1, p53, and TA-p73/p63, inhibits immune-inhibitory receptors/molecules, targets cancer stem cells, confers protection against chemoresistance and prolongs survival, via up-regulation of its target gene, 17/June/2019, 6.14 am https://genomediscovery.org/wp-content/uploads/2019/06/MND-functions-as-an-antitumor.metastasis-agent-by-increasing-the-expression-of-tumor.metastasis-suppressors-including-BIRC5-p12DOC1-p53.21-TA-p73.p63-and-INK4a.ARF_.jpg 1280 720 Dr Boomi's Genom-2-Discovery Center Dr Boomi's Genom-2-Discovery Center https://genomediscovery.org/wp-content/uploads/2019/06/MND-functions-as-an-antitumor.metastasis-agent-by-increasing-the-expression-of-tumor.metastasis-suppressors-including-BIRC5-p12DOC1-p53.21-TA-p73.p63-and-INK4a.ARF_.jpg June 17, 2019 June 17, 2019

What we say: On the foundation of this interesting finding, Dr L Boominathan PhD, the Director-cum-chief Scientist of GBMD, reports that: Probiotic-based chemotherapy targeting cancer stem cells and immune-inhibitory receptors…

June 17, 2019

Regenerative therapy for improving cognitive deficits in aged individuals: Chitosan, isolated from Shrimps and others, decreases vascular cell adhesion molecule 1 (VCAM 1), inhibits microglia activity, increases hippocampal neural precursor activity, ameliorates cognition, & attenuates age-related neurodegeneration, through up regulation of its target genes, 17/June/2019, 6.05 am

Regenerative therapy for improving cognitive deficits in aged individuals: Chitosan, isolated from Shrimps and others, decreases vascular cell adhesion molecule 1 (VCAM 1), inhibits microglia activity, increases hippocampal neural precursor activity, ameliorates cognition, & attenuates age-related neurodegeneration, through up regulation of its target genes, 17/June/2019, 6.05 am https://genomediscovery.org/wp-content/uploads/2019/06/Chitosan-attenuates-age-associated-decline-of-hippocambal-function-and-augments-learning-cognition-and-memory-in-the-aged-population-through-down-regulation-of-VCAM1.jpg3_.jpg 960 720 Dr Boomi's Genom-2-Discovery Center Dr Boomi's Genom-2-Discovery Center https://genomediscovery.org/wp-content/uploads/2019/06/Chitosan-attenuates-age-associated-decline-of-hippocambal-function-and-augments-learning-cognition-and-memory-in-the-aged-population-through-down-regulation-of-VCAM1.jpg3_.jpg June 17, 2019 June 17, 2019

Introduction: What they say A study from the Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA, VA Palo Alto Health Care System, Palo Alto,…

June 17, 2019

Probiotic-based chemotherapy targeting cancer stem cells and immune-inhibitory receptors in chronic lymphocytic leukemia (CLL) and advanced metastatic cancers: A pharmaceutical mixture encompassing Venetoclax and Ibrutinib (VAI) and probiotic Lactobacillus rhamnosus increases the expression of tumor suppressor genes, such as SMARCA4, KIBRA, p53, and TA-p73/p63, inhibits immune-inhibitory receptors/molecules, targets cancer stem cells, confers protection against chemoresistance and prolongs survival, and stalls CLL progression, via up-regulation of its target gene, 17/June/2019, 5.48 am

Probiotic-based chemotherapy targeting cancer stem cells and immune-inhibitory receptors in chronic lymphocytic leukemia (CLL) and advanced metastatic cancers: A pharmaceutical mixture encompassing Venetoclax and Ibrutinib (VAI) and probiotic Lactobacillus rhamnosus increases the expression of tumor suppressor genes, such as SMARCA4, KIBRA, p53, and TA-p73/p63, inhibits immune-inhibitory receptors/molecules, targets cancer stem cells, confers protection against chemoresistance and prolongs survival, and stalls CLL progression, via up-regulation of its target gene, 17/June/2019, 5.48 am https://genomediscovery.org/wp-content/uploads/2019/06/VAI-and-or-the-probiotic-Lactobacillus-increases-the-expression-of-SMARCA4-KIBRA-and-other-genes-and-attenuates-tumor-progression.jpg4_.jpg 1280 720 Dr Boomi's Genom-2-Discovery Center Dr Boomi's Genom-2-Discovery Center https://genomediscovery.org/wp-content/uploads/2019/06/VAI-and-or-the-probiotic-Lactobacillus-increases-the-expression-of-SMARCA4-KIBRA-and-other-genes-and-attenuates-tumor-progression.jpg4_.jpg June 17, 2019 June 17, 2019

Introduction: What they say A study from the University of Texas M.D. Anderson Cancer Center, Houston, USA shows that “Ibrutinib and Venetoclax for First-Line Treatment of CLL.” This research paper was published, in…

June 14, 2019

Sesame oil-derived compounds functions as a longevity promoter: Sesamin or Sesamol, derived from sesame oil or seeds, slows down cardiac aging, and increases lifespan, via up-regulation of BubR1 and others genes, 14/June/2019, 10.25 pm

Sesame oil-derived compounds functions as a longevity promoter: Sesamin or Sesamol, derived from sesame oil or seeds, slows down cardiac aging, and increases lifespan, via up-regulation of BubR1 and others genes, 14/June/2019, 10.25 pm https://genomediscovery.org/wp-content/uploads/2019/06/Sesamin-and-Sesamol-promote-longevity-through-induction-of-BUBR1.jpg2_.jpg3_.jpg 1280 720 Dr Boomi's Genom-2-Discovery Center Dr Boomi's Genom-2-Discovery Center https://genomediscovery.org/wp-content/uploads/2019/06/Sesamin-and-Sesamol-promote-longevity-through-induction-of-BUBR1.jpg2_.jpg3_.jpg June 14, 2019 June 14, 2019

What they say: Introduction: A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston, USA; and Department of Pharmacology,…

June 14, 2019

Natural product-based regenerative therapy for improving cognitive deficits in aged individuals: Sulforaphane, isolated from Broccoli and others, decreases vascular cell adhesion molecule 1 (VCAM 1), inhibits microglia activity, increases hippocampal neural precursor activity, ameliorates cognition, & attenuates age-related neurodegeneration, through up regulation of its target genes, 14/June/2019, 6.31 am

Natural product-based regenerative therapy for improving cognitive deficits in aged individuals: Sulforaphane, isolated from Broccoli and others, decreases vascular cell adhesion molecule 1 (VCAM 1), inhibits microglia activity, increases hippocampal neural precursor activity, ameliorates cognition, & attenuates age-related neurodegeneration, through up regulation of its target genes, 14/June/2019, 6.31 am https://genomediscovery.org/wp-content/uploads/2019/06/Sulforaphane-attenuates-age-associated-decline-of-hippocambal-function-and-augments-learning-cognition-and-memory-in-the-aged-population-through-down-regulation-of-VCAM1.jpg3_.jpg 960 720 Dr Boomi's Genom-2-Discovery Center Dr Boomi's Genom-2-Discovery Center https://genomediscovery.org/wp-content/uploads/2019/06/Sulforaphane-attenuates-age-associated-decline-of-hippocambal-function-and-augments-learning-cognition-and-memory-in-the-aged-population-through-down-regulation-of-VCAM1.jpg3_.jpg June 14, 2019 June 14, 2019

Sesame oil-derived compounds functions as a longevity promoter: Sesamin or Sesamol, derived from sesame oil or seeds, slows down cardiac aging, and increases lifespan, via up-regulation of BubR1 and others genes, 14/June/2019, 10.25 pm

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