Ideas

August 23, 2019

Published by admin_auro at August 23, 2019

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Combinatorial therapy for autoimmune diabetes (TIDM): A pharmaceutical mixture encompassing Dulaglutide (trade name: Trulicity), a Glucagon-like peptide-1 (GLP-1) receptor agonist, and Verapamil (brand name: Calanm, Isoptin and others), an anti-hypertensive drug, increases PD-L1 expression, increases Tregs function, promotes immune tolerance, increases pancreatic β-cell proliferation and regeneration, increases insulin secretion, improves insulin sensitivity, increases energy utilization, and reverses TIDM, via up-regulation of its target gene, 23/August/2019, 11.38 pm

Introduction: What they say A study from the International Center for T1D, Pediatric Clinical Research Center Romeo ed Enrica Invernizzi, “L. Sacco” Department of Biomedical and […]

August 23, 2019

Published by admin_auro at August 23, 2019

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Cancer
Ideas

Probiotic-based Chemotherapy (PCT) targeting cancer stem cells and immune-inhibitory receptors in relapsed chronic lymphocytic leukemia (CLL) and in advanced metastatic cancers: A pharmaceutical mixture encompassing Acalabrutinib, and probiotic Lactobacillus rhamnosus increases the expression of tumor suppressor genes, such as PDCD4, ACAT1, p53, and TA-p73/p63, inhibits immune-inhibitory receptors/molecules, targets cancer stem cells, confers protection against chemoresistance and prolongs survival, and stalls CLL progression, via up-regulation of its target gene, 23/August/2019, 10.39 pm

Introduction: What they say A study from the the Division of Hematology, Department of Internal Medicine, Ohio State University, and the Department of Veterinary Biosciences, College […]

August 21, 2019

Published by admin_auro at August 21, 2019

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Sunshine vitamin can extend lifespan: VitaminD3-based anti-ageing and Lifespan extension therapy: A pharmaceutical mixture encompassing 1, 25-DihyroxyvitaminD3/Calcitriol/Cholecalciferol increases CHIP levels, increases monoubiquitylation of insulin receptor (INSR), decreases INSR protein levels and enhances lifespan, via down regulation of its target gene, 21/August/2019, 2.43 pm

Introduction: What they say A study from Institute for Cell Biology, University of Bonn, Ulrich-Haberland Str. Bonn, Germany; and Institute for Genetics and CECAD Research Center, […]

August 20, 2019

Published by admin_auro at August 20, 2019

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Natural product-based curative therapy for autoimmune diabetes (TIDM): Repurposing the anti-malarial drug Artesunate into an anti-diabetic drug: Artesunate, a derivative of Artimesinin, which aids in the treatment of malaria, increases PD-L1 expression, increases Tregs function, promotes immune tolerance, increases pancreatic β-cell proliferation and regeneration, increases insulin secretion, improves insulin sensitivity, increases energy utilization, and reverses TIDM, via up-regulation of its target gene, 20/August/2019, 10.09 pm

Introduction: What they say A study from the International Center for T1D, Pediatric Clinical Research Center Romeo ed Enrica Invernizzi, “L. Sacco” Department of Biomedical and […]