Ideas

June 9, 2019
Published by admin_auro at June 9, 2019
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Probiotic-based chemotherapy targeting cancer stem cells and immune-inhibitory receptors in chronic lymphocytic leukemia (CLL) and advanced metastatic cancers: A pharmaceutical mixture encompassing Venetoclax and Ibrutinib (VAI) and probiotic Lactobacillus rhamnosus increases the expression of tumor suppressor genes, such as TIMP3, PTPN14, p53, and TA-p73/p63, inhibits immune-inhibitory receptors/molecules, targets cancer stem cells, confers protection against chemoresistance and prolongs survival, and stalls CLL progression, via up-regulation of its target gene, 09/June/2019, 6.23 pm

Introduction: What they say A study from the University of Texas M.D. Anderson Cancer Center, Houston, USA shows that “Ibrutinib and Venetoclax for First-Line Treatment of CLL.” This research […]
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June 8, 2019
Published by admin_auro at June 8, 2019
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Curing autoimmune diabetes  (TIDM) with commonly available blood pressure drug Carvedilol:  Carvedilol-based therapy for autoimmune diabetes: Carvedilol (brand name: Coreg and others),  a non-selective beta blocker used to treat high blood pressure and congestive heart failure, increases PD-L1 expression, increases Tregs function, promotes immune tolerance, increases pancreatic β-cell proliferation and regeneration, increases insulin secretion, improves insulin sensitivity, increases energy utilization, and reverses TIDM, via up-regulation of its target gene, 8/June/2019, 11.22 pm

Introduction: What they say A study from the International Center for T1D, Pediatric Clinical Research Center Romeo ed Enrica Invernizzi, “L. Sacco” Department of Biomedical and […]
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June 7, 2019
Published by admin_auro at June 7, 2019
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Natural product-derived combinatorial therapy for functional recovery after Myocardial Infarction and prevent cardiac failure: A pharmaceutical mixture encompassing Gambogic acid (GA) and (-)-EpiGalloCatechin-3-Gallate (EGCG) [GA+EGCG] inhibits DNA damage responses, induces telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction, via up regulation of PNUTS, Telomerase & MiR-199,  8/June/2019, 12.06 am

What they say:  A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published, in the 7 March  2013 issue of Nature,  by Prof Dimmler, […]
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June 7, 2019
Published by admin_auro at June 7, 2019
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Molecular therapy for body weight control, energy homeostasis and TIIDM: Aleglitazar, a PPARα and PPARγ agonist, inhibits DNA methyltransferase 3a (Dnmt3a) expression, increases FGF21 expression, augments insulin sensitivity, increases glucose tolerance, and protects from diet-induced obesity and TIIDM, via up-regulation of its target gene, 7/June/2019, 11.30 pm

Introduction: What they say  A study from Nutritional Sciences and Toxicology Department, University of California, Berkeley, Berkeley, United States shows that “Dnmt3a is an epigenetic mediator […]
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