Ideas

June 20, 2019
Published by admin_auro at June 20, 2019
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Eating ample amounts of fruit Pomegranate may extend your lifespan: Urolithin A (UA)-based combinatorial therapy for Lifespan extension: A therapeutic mix encompassing Urolithin A (UA), Melatonin, Ursolic acid, Maresin, DIM, Lutein, Ursolic acid  Lutein, Maresin, Cholecalciferol  Catalpol, Isoliquiritigenin (UAMUMDLCCI) activates autophagy, promotes leanness, increases insulin sensitivity, improves motor function, alleviates ageing feature and extends lifespan via upregulation of its target gene ATG5 (Autophagy-related 5), 20/June/2019, 3.51 pm

Introduction: What they say A study from the Global Research Laboratory, Seoul National University, Korea shows that “Overexpression of Atg5 in mice activates autophagy and extends lifespan.” This study was […]
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June 20, 2019
Published by admin_auro at June 20, 2019
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Probiotic-based chemotherapy targeting cancer stem cells and immune-inhibitory receptors in chronic lymphocytic leukemia (CLL) and in advanced metastatic cancers: A pharmaceutical mixture encompassing Venetoclax and Ibrutinib (VAI) and probiotic Lactobacillus rhamnosus increases the expression of tumor suppressor genes, such as HNF4α, PP2A, p53, and TA-p73/p63, inhibits immune-inhibitory receptors/molecules, targets cancer stem cells, confers protection against chemoresistance and prolongs survival, and stalls CLL progression, via up-regulation of its target gene, 20/June/2019, 7.33 am

Introduction: What they say A study from the University of Texas M.D. Anderson Cancer Center, Houston, USA shows that “Ibrutinib and Venetoclax for First-Line Treatment of CLL.” This research […]
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June 20, 2019
Published by admin_auro at June 20, 2019
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Mechanistic insights into how Liraglutide aids in remission of Diabetes: Liraglutide (brand name: Victoza, Saxenda and others), a  drug used in the treatment of type II diabetes, inhibits Amysin expression, increases insulin secretion, and decreases the risk of hyperglycemia, via downregulation of  Sox4 and its target gene Amysin,  20/June/2019, 7.13 am

Introduction: What they say  Nobel laureate [ in Physiology/Medicine in 1975] Prof. David Baltimore and his research team, from California Institute of Technology, California, USA, had reported in the September 14, […]
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June 18, 2019
Published by admin_auro at June 18, 2019
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Ciliary neurotrophic factor (CNTF)-based curative therapy for autoimmune diabetes (TIDM):  Ciliary neurotrophic factor (CNTF)  increases the expression of PD-L1, decreases the expression of TXNIP, augments Tregs function, promotes immune tolerance, increases pancreatic β-cell proliferation and regeneration, increases insulin secretion, improves insulin sensitivity, increases energy utilization, and reverses TIDM, via up regulation of its target gene, 18/June/2019, 10.56 pm

Introduction: What they say A study from the International Center for T1D, Pediatric Clinical Research Center Romeo ed Enrica Invernizzi, “L. Sacco” Department of Biomedical and Clinical […]
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