Ideas

Cardiac rejuvenation therapy: Oncofetal H19 RNA suppresses tumor suppressor INK4a/p16 expression, and inhibits dilated cardiomyopathy and heart failure via up regulation of its target gene, 9/January/2017, 11.12 pm

Cardiac rejuvenation therapy: Oncofetal H19 RNA suppresses tumor suppressor INK4a/p16 expression, and inhibits dilated cardiomyopathy and heart failure via up regulation of its target gene, 9/January/2017, 11.12 pm 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A recent study from the Stem Cell Aging Group, Centro Nacional de Investigaciones Cardiovasculares, E-28029 Madrid, Spain shows that “Bmi1 limits dilated cardiomyopathy and heart failure…

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Natural product therapy for glucose homeostasis and TIIDM: Oleanolic acid, found in Syzygium S. or Jawa apple and among others, increases Pax6 and insulin expression, decreases the levels of glucagon, ghrelin and Somatostatin, reduces metabolic stress, improves insulin sensisitity, promotes glucose homeostasis and prevents progression to TIIDM via down regulation of its target gene, 9/January/2017, 6.50 pm

Natural product therapy for glucose homeostasis and TIIDM: Oleanolic acid, found in Syzygium S. or Jawa apple and among others, increases Pax6 and insulin expression, decreases the levels of glucagon, ghrelin and Somatostatin, reduces metabolic stress, improves insulin sensisitity, promotes glucose homeostasis and prevents progression to TIIDM via down regulation of its target gene, 9/January/2017, 6.50 pm 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Department of Developmental Biology and Cancer Research, The Institute for Medical Research Israel-Canada, The Hebrew University-Hadassah Medical School, Jerusalem, Israel shows that…

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Molecular therapy for Myocardial Infarction: Saxagliptin (brand name: Onglyza), a hypoglycemic agent that functions as a dipeptidyl peptidase-4 (DPP-4) inhibitor, inhibits DNA damage responses, increases telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction via up-regulation of PNUTS, 9/January/2017, 9.30 pm

Molecular therapy for Myocardial Infarction: Saxagliptin (brand name: Onglyza), a hypoglycemic agent that functions as a dipeptidyl peptidase-4 (DPP-4) inhibitor, inhibits DNA damage responses, increases telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction via up-regulation of PNUTS, 9/January/2017, 9.30 pm 150 150 Dr Boomi's Genom-2-Discovery Center

What they say:  A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published in the 7 March  2013 issue of Nature  by Prof Dimmler, Boon, and others. What we…

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Natural product-derived therapy for Metastatic human tumors: Shikonin, one of the main components in Lithospermum erythrorhizon, decreases the expression of c-Src protein, inhibits the expression of a number of enzymes of glycolysis, and suppresses proliferation, migration, invasion, tumorigenesis and metastasis via up regulation of its target gene,9/January/2017, 6.18 am

Natural product-derived therapy for Metastatic human tumors: Shikonin, one of the main components in Lithospermum erythrorhizon, decreases the expression of c-Src protein, inhibits the expression of a number of enzymes of glycolysis, and suppresses proliferation, migration, invasion, tumorigenesis and metastasis via up regulation of its target gene,9/January/2017, 6.18 am 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say: A study from the State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, Fujian 361102,…

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Cardiac rejuvenation therapy: SNAI2/SLUG, a protein that promotes epithelial-to-mesenchymal transition, suppresses tumor suppressor INK4a/p16 expression, and inhibits dilated cardiomyopathy and heart failure via up regulation of its target gene, 8/January/2017, 11.58 pm

Cardiac rejuvenation therapy: SNAI2/SLUG, a protein that promotes epithelial-to-mesenchymal transition, suppresses tumor suppressor INK4a/p16 expression, and inhibits dilated cardiomyopathy and heart failure via up regulation of its target gene, 8/January/2017, 11.58 pm 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A recent study from the Stem Cell Aging Group, Centro Nacional de Investigaciones Cardiovasculares, E-28029 Madrid, Spain shows that “Bmi1 limits dilated cardiomyopathy and heart failure…

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Life-extension therapy: Asprin (acetylsalicylic acid (ASA), one of the commonly used drugs in the treatment of Pain, fever and inflammation, inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span, 8/January/2017, 11.41 pm

Life-extension therapy: Asprin (acetylsalicylic acid (ASA), one of the commonly used drugs in the treatment of Pain, fever and inflammation, inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span, 8/January/2017, 11.41 pm 150 150 Dr Boomi's Genom-2-Discovery Center

What they say? A study from the Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK shows that “Ribosomal protein S6 kinase 1…

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