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Ideas

April 9, 2017

Natural product-derived therapy for Metastatic cancers: Shikonin, found in Zicao, among others, decreases the expression of metastasis promoters ZBTB2 and PPM1F, inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up regulation of its target gene, 9/April/2017, 11.20 pm

From Significance of the study to Public health relevance: Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more […]
April 9, 2017

Natural product-derived antiviral therapy against Neuroinvasive West Nile virus: Rhamnetin, an O-methylated flavonol found in Cloves, increases the expression of RIPK3, promotes chemokines production, inhibits neuroinflammation, and restricts neuroinvasive West Nile virus production and pathogenesis in neurons via up regulation of its target gene, 9/April/2017, 11. 10 pm

Introduction: What they say A study from the Department of Immunology, University of Washington, Seattle, WA 98109, USA; Center for Innate Immunity and Immune Disease, University […]
April 9, 2017

Natural product-derived regenerative therapy for reversing diabetes: Oleanolic acid, found in Syzygium S. or Jawa apple, and Prosopis glandulosa and among others, increases the expression of Sox17, Sox2, Pdx-1, and Ngn3, decreases mTOR expression, promotes regeneration of insulin-producing ß cells, increases insulin secretion, promotes glucose homeostasis and reverses T1D and T2D via down regulation of its target gene, 9/April/2017, 6.51 pm

Introduction: What they say A study from the Longevity Institute, School of Gerontology, Department of Biological Sciences, University of Southern California, 3715 McClintock Avenue, Los Angeles, […]
April 8, 2017

Natural product-derived antiviral therapy against Neuroinvasive West Nile virus: Luteolin, a flavonoid found in Salvia tomentosa, Perilla, thyme, among others, increases the expression of RIPK3, promotes chemokines production, inhibits neuroinflammation, and restricts neuroinvasive West Nile virus production and pathogenesis in neurons via up regulation of its target gene, 8/April/2017, 11.38 pm

Introduction: What they say A study from the Department of Immunology, University of Washington, Seattle, WA 98109, USA; Center for Innate Immunity and Immune Disease, University […]
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