Ideas

August 24, 2017

Natural product-derived therapy for Chronic Myeloid leukaemia (CML): a therapeutic mix encompassing Ivermectin and Curcumin decreases the expression of Musashi2, inhibits cytosolic aminotransferase BCAT1 expression, decreases the intracellular production of BCAAs (Branched-chain amino acids), increases the expression of tumor suppressor genes, promotes differentiation of CML cells, and inhibits cancer progression in Myeloid leukemia via up-regulation of its target gene, 25/August/2017, 4.35 am

Introduction: What they say: A study from the Department of Biochemistry-Molecular Biology, Franklin College of Arts and Sciences, The University of Georgia, Athens, Georgia 30602, USA; […]
August 23, 2017

 Natural product therapy for pulmonary arterial hypertension: Astaxanthin (Asx) inhibits the development of pulmonary arterial hypertension via down regulation of its target gene Notch3, 24/August/2017, 2.01 am

What they say:  A study from the University of California, La Jolla, California, USA shows that “Notch3 signaling promotes the development of pulmonary arterial hypertension.” This study was published in the 15 November  2009 issue of the journal “Nature Medicine”[the […]
August 23, 2017

Natural product-based therapy for Cardiomyopathy: Punicalagin (PN), isolated from Punica Granutum (PG)/Pomegranate, decreases the expression of Sox6, restores the balance between slow- and fast-twitch myofiber proteins and alleviates Cardiomyopathy via up regulation of its target gene, 24/August/2017,  1.17 am

Introduction: What they say A recent study from the Department of Cardiology, Boston Children’s Hospital, Harvard Medical School, Boston, Massachusetts, USA; and Harvard Stem Cell Institute, Harvard University, Cambridge, Massachusetts, USA shows that “Trbp regulates heart […]
August 23, 2017

Natural product-derived combinatorial therapy for therapy-resistant cancers: A therapeutic mix encompassing Berberine (BER), Gambogic acid and Curcumin (BGC) inhibits the expression of phospholipid glutathione peroxidase (GPX4), inhibits GPX4 signaling network and lipid peroxidase pathway, suppresses EMT protein ZEB1, increases sensitivity to anticancer therapy and prolongs survival via up regulation of its target gene, 24/August/2017, 12.33 am

Introduction: What they say: A study from Broad Institute, Cambridge, Massachusetts, USA, Howard Hughes Medical Institute, Chevy Chase, Maryland and Department of Chemistry and Chemical Biology, […]
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