Ideas

Cardiac rejuvenation therapy: Secreted protein acidic and rich in cysteine (SPARC/osteonectin/BM-40) suppresses tumor suppressor INK4a/p16 expression, and inhibits dilated cardiomyopathy and heart failure via up regulation of its target gene, 31/December/2016, 11.25 am
Cardiac rejuvenation therapy: Secreted protein acidic and rich in cysteine (SPARC/osteonectin/BM-40) suppresses tumor suppressor INK4a/p16 expression, and inhibits dilated cardiomyopathy and heart failure via up regulation of its target gene, 31/December/2016, 11.25 am 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A recent study from the Stem Cell Aging Group, Centro Nacional de Investigaciones Cardiovasculares, E-28029 Madrid, Spain shows that “Bmi1 limits dilated cardiomyopathy and heart failure…

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Natural product-derived therapy for Human Leukemias: Ginsenoside, one of components in American ginseng herb, found in stem of Caulis clematidis armandii and Hibiscus ficulneus, suppresses B-Cell and myeloid leukemias via up regulation of the tumor suppressor IRF4, 30/December/2016, 10.28 am
Natural product-derived therapy for Human Leukemias: Ginsenoside, one of components in American ginseng herb, found in stem of Caulis clematidis armandii and Hibiscus ficulneus, suppresses B-Cell and myeloid leukemias via up regulation of the tumor suppressor IRF4, 30/December/2016, 10.28 am 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say Noble laureate in Physiology/Medicine (1975) Prof. David Baltimore, from California Institute of Technology, California, USA, had reported in the July 8, 2014 issue of the Journal “Blood” that: “Dual mechanisms by which MiR-125b represses IRF4 to…

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Anti-telomerase cancer therapy: LRRC4/NGL-2 (Leucine rich repeat containing 4/Netrin-G ligand-2) suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) and inhibits cancer progression via down-regulation of it target gene, 30/December/2016, 9.43 am
Anti-telomerase cancer therapy: LRRC4/NGL-2 (Leucine rich repeat containing 4/Netrin-G ligand-2) suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) and inhibits cancer progression via down-regulation of it target gene, 30/December/2016, 9.43 am 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say:   The 1989 Nobel prize winner in Chemistry, Prof. Thomas R. Cech from the BioFrontiers Institute, USA has published a research paper in the 13 December 2012 issue of the Nature journal (492(7428):285-9; and I.F: >42) stating that “The TEL patch of telomere protein TPP1…

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Natural product-derived Cardiac rejuvenation therapy: Kaempferol, found in Allium cepa, Aloe vera, Coccinia grandis, Moringa oleifera, & Rosmarinus officinalis among others, suppresses tumor suppressor INK4a/p16 expression, and inhibits dilated cardiomyopathy and heart failure via up regulation of its target gene, 30/December/2016, 7.15 am
Natural product-derived Cardiac rejuvenation therapy: Kaempferol, found in Allium cepa, Aloe vera, Coccinia grandis, Moringa oleifera, & Rosmarinus officinalis among others, suppresses tumor suppressor INK4a/p16 expression, and inhibits dilated cardiomyopathy and heart failure via up regulation of its target gene, 30/December/2016, 7.15 am 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A recent study from the Stem Cell Aging Group, Centro Nacional de Investigaciones Cardiovasculares, E-28029 Madrid, Spain shows that “Bmi1 limits dilated cardiomyopathy and heart failure…

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Life-extension therapy: PAPD5 (Poly(A) RNA Polymerase D5, Non-Canonical) inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span, 29/December/2016, 10. 54 pm
Life-extension therapy: PAPD5 (Poly(A) RNA Polymerase D5, Non-Canonical) inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span, 29/December/2016, 10. 54 pm 150 150 Dr Boomi's Genom-2-Discovery Center

What they say? A recent study from the Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK shows that “Ribosomal protein S6 kinase…

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Molecular therapy for Myocardial Infarction: Ambrisentan, a drug used in the treatment of Pulmonary hypertension, inhibits DNA damage responses, increases telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction via up-regulation of PNUTS, 29/December/2016, 10.22 pm
Molecular therapy for Myocardial Infarction: Ambrisentan, a drug used in the treatment of Pulmonary hypertension, inhibits DNA damage responses, increases telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction via up-regulation of PNUTS, 29/December/2016, 10.22 pm 150 150 Dr Boomi's Genom-2-Discovery Center

What they say:  A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published in the 7 March  2013 issue of Nature  by Prof Dimmler, Boon, and others. What we…

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