Ideas

September 8, 2017

Published by admin_auro at September 8, 2017

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Cancer
Ideas

Molecular therapy for Metastatic cancers: Geniposide, isolated from Gardenia, increases the expression of tumor suppressors TPM1 and TAp63, inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up regulation of its target gene, 9/September/2017, 1.37 am

From Significance of the study to Public health relevance: Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more […]

September 8, 2017

Published by admin_auro at September 8, 2017

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Natural product therapy for Diabetic nephropathy (DN): Artesunate, isolated from Artemisia annua L, increases Pyruvate kinase M2 (PKM2) expression, decreases toxic glucose metabolites, mitochondrial dysfunction and apoptosis, augments glycolytic flux and PGC-1α levels, improves metabolic abnormalities, albuminuria, glomerular pathology, and renal dysfunction and alleviates diabetic nephropathy via down regulation of its target gene, 9/September/2017, 1.24 am

Introduction: What they say A study from the Research Division, Joslin Diabetes Center, Harvard Medical School, Boston, Massachusetts, USA shows that “Pyruvate kinase M2 activation may […]

September 8, 2017

Published by admin_auro at September 8, 2017

Categories

Ideas
Stroke

Natural product-derived therapy for Stroke: β-Cryptoxanthin, Sweet peppers, among others, attenuates hippocampal neurons injury, augments regenerative neurogenesis after Ischemic Stroke, and ameliorates stroke damage and neurological deficits via up regulation of its target genes BDNF and NAMPT, 9/September/2017, 1.01 am

Introduction: What they say A recent study from Research Center for Neurobiology and Department of Neurobiology, Xuzhou Medical College, 209 Tongshan Road, Xuzhou, Jiangsu 221004, PR China; […]

September 8, 2017

Published by admin_auro at September 8, 2017

Categories

Natural product-based therapy for anxiety and depression: Geniposide, isolated from Gardenia, increases PHF8 levels, augments the expression of serotonin receptors Htr1a and Htr2a, and promotes resistance to stress-induced -anxiety and -depression via down regulation of its target gene, 9/September/2017, 12.07 am

Introduction: What they say: A study from Department of Molecular Biology, Cancer Center and Center for Regenerative Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA; Department […]