Ideas

Oats as a longevity-promoting agent: Avenanthramide A, derived from Oats, inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span, via up regulation of its target gene, 14/April/2019, 3.49 pm
Oats as a longevity-promoting agent: Avenanthramide A, derived from Oats, inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span, via up regulation of its target gene, 14/April/2019, 3.49 pm 1280 720 Dr Boomi's Genom-2-Discovery Center

What they say?  A study from the Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK shows that “Ribosomal protein S6 kinase 1…

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Embryo-derived peptide may aid in the treatment of regenerative muscle atrophy: Synthetic preimplantation factor (sPIF) increases the expression of IGF-1, PI3K(p85a) and B-Myb, decreases the expression of tumor suppressors, promotes regeneration of muscle cells, and reverses muscle atrophy via up regulation of its target gene, 14/April/2019, 3.25 pm
Embryo-derived peptide may aid in the treatment of regenerative muscle atrophy: Synthetic preimplantation factor (sPIF) increases the expression of IGF-1, PI3K(p85a) and B-Myb, decreases the expression of tumor suppressors, promotes regeneration of muscle cells, and reverses muscle atrophy via up regulation of its target gene, 14/April/2019, 3.25 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Cardiac Regeneration and Ageing Lab, School of Life Science, Shanghai University, Shanghai 200444, China shows that “miR-29b contributes to multiple types of…

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Mechanistic insights into why premenopausal women have lower incidence of TIIDM: Estradiol/17-β Estradiol-based therapy for Diabetes Mellitus: Estradiol/17-β Estradiol augments the expression of FGF19 and FGF1,  attenuates hepatic glucose production, decreases hepatic acetyl CoA content, brings down the levels of plasma ACTH, and corticosterone, augments insulin sensitivity, promotes weight loss and alleviates TIDM, via upregulation of its target gene, 14/April/2019, 8.24 am
Mechanistic insights into why premenopausal women have lower incidence of TIIDM: Estradiol/17-β Estradiol-based therapy for Diabetes Mellitus: Estradiol/17-β Estradiol augments the expression of FGF19 and FGF1,  attenuates hepatic glucose production, decreases hepatic acetyl CoA content, brings down the levels of plasma ACTH, and corticosterone, augments insulin sensitivity, promotes weight loss and alleviates TIDM, via upregulation of its target gene, 14/April/2019, 8.24 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say  A study from Diabetes and Obesity Center of Excellence, Department of Medicine, University of Washington, Seattle, Washington, USA shows that Central injection of FGF1 induces sustained…

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Ribonucleic acid-based combination therapy for Diabetic retinopathy: A pharmaceutical mixture encompassing  LncRNA MEG3, Epicatechin and Matrine (MEG3EM)  inhibits Soluble epoxide hydrolase (sEH) expression, decreases toxic 19,20-dihydroxydocosapentaenoic acid levels, inhibits pericyte loss, vascular permeability, and inflammation of the eye and progression of diabetic retinopathy, via down regulation of its target gene, 14/April/2019,  6.23 am
Ribonucleic acid-based combination therapy for Diabetic retinopathy: A pharmaceutical mixture encompassing  LncRNA MEG3, Epicatechin and Matrine (MEG3EM)  inhibits Soluble epoxide hydrolase (sEH) expression, decreases toxic 19,20-dihydroxydocosapentaenoic acid levels, inhibits pericyte loss, vascular permeability, and inflammation of the eye and progression of diabetic retinopathy, via down regulation of its target gene, 14/April/2019,  6.23 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Institute for Vascular Signalling, Centre for Molecular Medicine, Goethe University, Frankfurt am Main, Germany; and German Centre for Cardiovascular Research (DZHK) partner…

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Embryo-derive peptide may aid in the treatment of muscle atrophy and wasting:  Synthetic Preimplantation factor (sPIF) increases the expression of FGF19 and its receptor ß-Klotho, phosphorylates ERK1/2 and S6K1, decreases the expression of tumor suppressors  genes, promotes regeneration of muscle cells and hypertrophy of skeletal muscle, and reverses muscular atrophy and wasting via upregulation of its target gene, 14/April/2018, 12.09 am
Embryo-derive peptide may aid in the treatment of muscle atrophy and wasting:  Synthetic Preimplantation factor (sPIF) increases the expression of FGF19 and its receptor ß-Klotho, phosphorylates ERK1/2 and S6K1, decreases the expression of tumor suppressors  genes, promotes regeneration of muscle cells and hypertrophy of skeletal muscle, and reverses muscular atrophy and wasting via upregulation of its target gene, 14/April/2018, 12.09 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from Department of Biology, University of Bergen, Bergen, Norway; and Univ-Lyon, CarMeN Laboratory, INSERM 1060, INRA 1397, Université Claude Bernard Lyon, INSA Lyon, Oullins,…

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Oats-derived compound functions as an anti-HIV agent: A pharmaceutical mixture encompassing Avenanthramide-A  increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production, via upregulation of its target gene, 13/April/2019, 11.56 pm
Oats-derived compound functions as an anti-HIV agent: A pharmaceutical mixture encompassing Avenanthramide-A  increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production, via upregulation of its target gene, 13/April/2019, 11.56 pm 1280 720 Dr Boomi's Genom-2-Discovery Center

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that:  Oats-derived compound functions as an anti-HIV agent: A pharmaceutical mixture encompassing Avenanthramide-A  increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation…

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