Embryo-derive peptide may aid in the treatment of muscle atrophy and wasting:  Synthetic Preimplantation factor (sPIF) increases the expression of FGF19 and its receptor ß-Klotho, phosphorylates ERK1/2 and S6K1, decreases the expression of tumor suppressors  genes, promotes regeneration of muscle cells and hypertrophy of skeletal muscle, and reverses muscular atrophy and wasting via upregulation of its target gene, 14/April/2018, 12.09 am