Ideas

Natural product Immune enhancement therapy: (+)-Syringaresinol, isolated from Panax ginseng berry, and Prunus mume, among others, increases SOX2 expression and promotes innate immunity against bacterial infection via down-regulation of its target gene, 11/November/2016, 11.04 am
Natural product Immune enhancement therapy: (+)-Syringaresinol, isolated from Panax ginseng berry, and Prunus mume, among others, increases SOX2 expression and promotes innate immunity against bacterial infection via down-regulation of its target gene, 11/November/2016, 11.04 am 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say:  A recent study from the Institute of Biophysics, Chinese Academy of Sciences, Beijing, China shows that “Sox2 functions as a sequence-specific DNA sensor in neutrophils to initiate innate immunity…

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Small molecule-based therapy for Myocardial Infarction: Amifostine/Ethyol, a cytoprotective adjuvant, improves myocardial function after myocardial infarction via up-regulation of PNUTS, 14/November/2016, 10.55 am
Small molecule-based therapy for Myocardial Infarction: Amifostine/Ethyol, a cytoprotective adjuvant, improves myocardial function after myocardial infarction via up-regulation of PNUTS, 14/November/2016, 10.55 am 150 150 Dr Boomi's Genom-2-Discovery Center

What they say:  A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published in the 7 March  2013 issue of Nature  by Prof Dimmler, Boon, and others. What we…

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Natural product-based anti-ageing therapy: Avicularin , found in Taxillus kaempferi, Rhododendron aureum, and Polygonum aviculare, among others, increases NMN levels, decreases age-associated weight gain, augments energy metabolism, improves physical activity and insulin sensitivity, promotes healthy lipid profile, and improves eye function via down regulation of its target gene, 13/November/2016, 1.13 pm
Natural product-based anti-ageing therapy: Avicularin , found in Taxillus kaempferi, Rhododendron aureum, and Polygonum aviculare, among others, increases NMN levels, decreases age-associated weight gain, augments energy metabolism, improves physical activity and insulin sensitivity, promotes healthy lipid profile, and improves eye function via down regulation of its target gene, 13/November/2016, 1.13 pm 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from Gladstone Institute of Neurological Disease and Department of Neurology, University of California, San Francisco, San Francisco, CA 94158, USA and Department of Developmental…

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Natural product Life-span extension therapy: (+)-Syringaresinol, isolated from Panax ginseng berry, & Prunus mume, among others, increases life span by suppressing mTOR pathway through up regulation of its target gene, 13/November/2016, 11.26 am
Natural product Life-span extension therapy: (+)-Syringaresinol, isolated from Panax ginseng berry, & Prunus mume, among others, increases life span by suppressing mTOR pathway through up regulation of its target gene, 13/November/2016, 11.26 am 150 150 Dr Boomi's Genom-2-Discovery Center

What is known: It has been shown earlier that decreasing the expression/activity of mTOR increases overall mammalian lifespan, suggesting that mTOR inhibitors may function as “longevity promoters” From research findings…

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Natural product therapy for KRAS-mutant lung cancer: Epigallocatechin gallate, one of the main components of Green tea, decreases the expression of XPO1, increases the level of NFKBIA, inhibits NFKB transcriptional activity and suppresses the progression of KRAS-mutant lung cancer via up regulation of its target gene, 13/November/2016, 9.20 am
Natural product therapy for KRAS-mutant lung cancer: Epigallocatechin gallate, one of the main components of Green tea, decreases the expression of XPO1, increases the level of NFKBIA, inhibits NFKB transcriptional activity and suppresses the progression of KRAS-mutant lung cancer via up regulation of its target gene, 13/November/2016, 9.20 am 150 150 Dr Boomi's Genom-2-Discovery Center

What they say:  A recent study from the Department of Cell Biology, University of Texas Southwestern Medical Center, Texas 75390, USA shows that XPO1 can be pharmacologically targeted in KRAS-mutant lung cancer.…

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MiRNA-based therapy for Breast Cancer: MiRNA-137 increases the level of tumor suppressor p53, inhibits the proliferation of tumor-initiating cells in breast cancer, suppresses the progression of metastatic breast cancer, and supports tumor relapse-free survival in breast cancer patients, 13/November/2015, 9.01 am
MiRNA-based therapy for Breast Cancer: MiRNA-137 increases the level of tumor suppressor p53, inhibits the proliferation of tumor-initiating cells in breast cancer, suppresses the progression of metastatic breast cancer, and supports tumor relapse-free survival in breast cancer patients, 13/November/2015, 9.01 am 150 150 Dr Boomi's Genom-2-Discovery Center

What they say:  A study from the Division of Molecular Medicine and Genetics, Department of Internal Medicine, The Life Sciences Institute, University of Michigan, Ann Arbor, Michigan 48109, USA shows…

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