Ideas

Anti-inflammatory therapy for upper respiratory tract inflammatory diseases: SMG7, a protein known to play a role in nonsense-mediated mRNA decay, increases the expression of negative regulator of inflammation MyD88(s), inhibits pro-inflammatory mediators in lungs, and alleviates the common respiratory pathogen nontypeable Haemophilus influenzae (NTHi)-exacerbated asthma & chronic obstructive pulmonary disease via up-regulation of its target gene, 14/November/2015, 10.10 pm
Anti-inflammatory therapy for upper respiratory tract inflammatory diseases: SMG7, a protein known to play a role in nonsense-mediated mRNA decay, increases the expression of negative regulator of inflammation MyD88(s), inhibits pro-inflammatory mediators in lungs, and alleviates the common respiratory pathogen nontypeable Haemophilus influenzae (NTHi)-exacerbated asthma & chronic obstructive pulmonary disease via up-regulation of its target gene, 14/November/2015, 10.10 pm 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say:  A study from the Center for Inflammation, Immunity & Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA, 30303, USA shows that: “Resveratrol suppresses NTHi-induced…

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Natural product Life-span extension therapy: Amifostine/Ethyol increases life span by suppressing mTOR pathway through up regulation of its target gene, 14/November/2016, 10.02 pm
Natural product Life-span extension therapy: Amifostine/Ethyol increases life span by suppressing mTOR pathway through up regulation of its target gene, 14/November/2016, 10.02 pm 150 150 Dr Boomi's Genom-2-Discovery Center

What is known: It has been shown earlier that decreasing the expression/activity of mTOR increases overall mammalian lifespan, suggesting that mTOR inhibitors may function as “longevity promoters” From research findings…

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Molecular therapy for Regenerating the lost pancreatic β-cells in Diabetic patients: USP7/HAUSP promotes an insulin-sensitized state via up-regulation of reprogramming protein Lin28, 14/November/2016, 9.55 pm
Molecular therapy for Regenerating the lost pancreatic β-cells in Diabetic patients: USP7/HAUSP promotes an insulin-sensitized state via up-regulation of reprogramming protein Lin28, 14/November/2016, 9.55 pm 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say:  A study from the Stem Cell Transplantation Program, Division of Pediatric Hematology/Oncology, Boston Children’s Hospital and Dana-Farber Cancer Institute, Boston, Massachusetts, USA shows that “The Lin28/let-7 axis regulates glucose…

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Natural product therapy for triple-negative breast tumors: Emodin (EMD) (1,3,8-trihydroxy-6-methylanthraquinone), found in rhubarb, buckthorn and Japanese knotweed, increases the levels of cell cycle inhibitor, p27, inhibits pro-survival pathways mediated by c-Myc, and inhibits the progression of triple-negative breast cancer via up-regulation of its target gene, 14/November/2015, 9.45 pm
Natural product therapy for triple-negative breast tumors: Emodin (EMD) (1,3,8-trihydroxy-6-methylanthraquinone), found in rhubarb, buckthorn and Japanese knotweed, increases the levels of cell cycle inhibitor, p27, inhibits pro-survival pathways mediated by c-Myc, and inhibits the progression of triple-negative breast cancer via up-regulation of its target gene, 14/November/2015, 9.45 pm 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Department of Cell and Tissue Biology, University of California, San Francisco (UCSF), San Francisco, California, USA shows that “PIM1 kinase inhibition as…

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Natural product therapy for Bone disorders: Neem leaf extract inhibits the expression of Tgif2 and suppresses osteoporosis and bone metastasis via up-regulation of its target gene, 14/November/2016, 9.18 pm
Natural product therapy for Bone disorders: Neem leaf extract inhibits the expression of Tgif2 and suppresses osteoporosis and bone metastasis via up-regulation of its target gene, 14/November/2016, 9.18 pm 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction:  A study from the Department of Pharmacology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA has reported that “miR-34a blocks osteoporosis and bone metastasis by inhibiting osteoclastogenesis and Tgif2.”…

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Natural product therapy for Breast Cancer: γ-Bisabolene, one of the components in Cardamom, Cubeb, lemon, and Oregano, among others, increases the levels of tumor suppressor p53, decreases the expression of metastasis promoter Snail1, inhibits the proliferation of tumor-initiating cells, suppresses epithelial-to-mesenchymal transition and the progression of metastasis, and supports tumor relapse-free survival in breast cancer patients, 14/November/2015, 11.40 am
Natural product therapy for Breast Cancer: γ-Bisabolene, one of the components in Cardamom, Cubeb, lemon, and Oregano, among others, increases the levels of tumor suppressor p53, decreases the expression of metastasis promoter Snail1, inhibits the proliferation of tumor-initiating cells, suppresses epithelial-to-mesenchymal transition and the progression of metastasis, and supports tumor relapse-free survival in breast cancer patients, 14/November/2015, 11.40 am 150 150 Dr Boomi's Genom-2-Discovery Center

What they say:  A study from the Division of Molecular Medicine and Genetics, Department of Internal Medicine, The Life Sciences Institute, University of Michigan, Ann Arbor, Michigan 48109, USA shows…

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