Ideas

Natural product Anti-telomerase cancer therapy: Moringa oleifera (MO) extract suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) and inhibits cancer progression via down-regulation of its target gene, 22/October/2016, 7.05 am
Natural product Anti-telomerase cancer therapy: Moringa oleifera (MO) extract suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) and inhibits cancer progression via down-regulation of its target gene, 22/October/2016, 7.05 am 150 150 Dr Boomi's Genom-2-Discovery Center

The 1989 Nobel prize winner in Chemistry, Prof. Thomas R. Cech from the BioFrontiers Institute, USA has published a research paper in the 13 December 2012 Nature (492(7428):285-9; and I.F: >42) stating that “The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity.”  This study provides mechanistic insights…

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MiRNA therapy for Myocardial dysfunction: MiR-765 increases CDK inhibitor p27 expression, inhibits mTOR pathway, promotes autophagy in myocardial cells and prevents myocardial dysfunction via down-regulation of its target gene, 22/October/2016, 6.51 am
MiRNA therapy for Myocardial dysfunction: MiR-765 increases CDK inhibitor p27 expression, inhibits mTOR pathway, promotes autophagy in myocardial cells and prevents myocardial dysfunction via down-regulation of its target gene, 22/October/2016, 6.51 am 150 150 Dr Boomi's Genom-2-Discovery Center

Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports here that: MiRNA therapy for Myocardial dysfunction: MiR-765 increases CDK inhibitor p27 expression, inhibits mTOR pathway, promotes autophagy in myocardial cells and prevents…

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Natural product therapy for tuberculosis: Fructus Ligustri Lucide extract increases the expression of MKP-1, inhibits TLR2 signalling, secretion of Chemokine CXCL5, and recruitment of polymorphonuclear leukocytes (PMNs), decreases destructive pulmonary inflammation , promotes M. tuberculosis clearance and inhibits pulmonary tuberculosis via up-regulation of its target gene, 21/October/2016, 5.03 pm
Natural product therapy for tuberculosis: Fructus Ligustri Lucide extract increases the expression of MKP-1, inhibits TLR2 signalling, secretion of Chemokine CXCL5, and recruitment of polymorphonuclear leukocytes (PMNs), decreases destructive pulmonary inflammation , promotes M. tuberculosis clearance and inhibits pulmonary tuberculosis via up-regulation of its target gene, 21/October/2016, 5.03 pm 150 150 Dr Boomi's Genom-2-Discovery Center

A study from the Max Plank Institute for Infection Biology, Berlin, Germany shows that “CXCL5-secreting pulmonary epithelial cells drive destructive neutrophilic inflammation in tuberculosis.” This study was published in the…

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Natural product therapy for aged patients with Myocardial Infarction: Berberine, an isoquinoline alkaloid isolated from Phellodendron amurense, and Tinospora cordifolia, induces autophagy in cardiomyocytes, inhibits cardiomyocyte hypertrophy, improves myocardial function in Post myocardial-infarction patients via up-regulation of PPAR-α, PNUTS/PPP1R10 and Sirutin1, 21/October/2016, 1.31 pm
Natural product therapy for aged patients with Myocardial Infarction: Berberine, an isoquinoline alkaloid isolated from Phellodendron amurense, and Tinospora cordifolia, induces autophagy in cardiomyocytes, inhibits cardiomyocyte hypertrophy, improves myocardial function in Post myocardial-infarction patients via up-regulation of PPAR-α, PNUTS/PPP1R10 and Sirutin1, 21/October/2016, 1.31 pm 150 150 Dr Boomi's Genom-2-Discovery Center

A recent study from the Institute of Molecular and Translational Therapeutic Strategies, Hannover Medical School, Hannover, Germany; Excellence Cluster REBIRTH, Hannover Medical School, Hannover, Germany; and National Heart and Lung…

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Natural product anti-inflammatory therapy for upper respiratory tract inflammatory diseases: Hyperoside, found in Drosera Rotundifolia and Prunella vulgaris (Common self-heal), increases the expression of negative regulator of inflammation MyD88(s), inhibits pro-inflammatory mediators in lungs, and alleviates the common respiratory pathogen nontypeable Haemophilus influenzae (NTHi)-exacerbated asthma & chronic obstructive pulmonary disease via up-regulation of its target gene, 21/October/2015, 7.55 am
Natural product anti-inflammatory therapy for upper respiratory tract inflammatory diseases: Hyperoside, found in Drosera Rotundifolia and Prunella vulgaris (Common self-heal), increases the expression of negative regulator of inflammation MyD88(s), inhibits pro-inflammatory mediators in lungs, and alleviates the common respiratory pathogen nontypeable Haemophilus influenzae (NTHi)-exacerbated asthma & chronic obstructive pulmonary disease via up-regulation of its target gene, 21/October/2015, 7.55 am 150 150 Dr Boomi's Genom-2-Discovery Center

A study from the Center for Inflammation, Immunity &Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA, 30303, USA shows that: “Resveratrol suppresses NTHi-induced inflammation via up-regulation of the…

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Molecular therapy for Myocardial dysfunction: Metformin, one of the widely used drugs in the treatment of TIIDM, increases CDK inhibitor p27 expression, inhibits mTOR pathway, promotes autophagy in myocardial cells and prevents myocardial dysfunction via down-regulation of its target gene, 21/October/2016, 6.15 am
Molecular therapy for Myocardial dysfunction: Metformin, one of the widely used drugs in the treatment of TIIDM, increases CDK inhibitor p27 expression, inhibits mTOR pathway, promotes autophagy in myocardial cells and prevents myocardial dysfunction via down-regulation of its target gene, 21/October/2016, 6.15 am 150 150 Dr Boomi's Genom-2-Discovery Center

Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports here that: Molecular therapy for Myocardial dysfunction: Metformin, one of the widely used drugs in the treatment of TIIDM, increases CDK inhibitor p27…

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