Ideas

July 18, 2017

Published by admin_auro at July 18, 2017

Categories

Polyamine-derived therapy for Regenerating the lost cardiomyocytes in Myocardial patients: Spermidine, found in Soy and mushroom among others, increases the expression of ERBB2/Her2 and promotes dedifferentiation of cardiomyocytes via down regulation of its target gene, 19/July/2017, 12.12 am

Introduction: What they say A recent study from the Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel shows that “ERBB2 triggers mammalian heart regeneration by promoting cardiomyocyte dedifferentiation and proliferation.” This study was […]

July 18, 2017

Published by admin_auro at July 18, 2017

Categories

Cancer
Ideas

Natural product-derived therapy for prostate cancer: Dihydroartemisinin(DHA), a derivative of Artemisinin present in Artemesia Annua L, inhibits the expression of mTORC1 and its downstream target AMD1, dismantles mTORC1-AMD1 signaling network, decreases polyamine levels, and inhibits prostate cancer progression via up regualtion of its target gene, 18/July/2017, 11.53 pm

Introduction: What they say: A study from CIC bioGUNE (Center for Cooperative Research in Biosciences), Bizkaia Technology Park, 801 Building, 48160 Derio, Spain shows that “mTORC1-dependent AMD1 regulation sustains polyamine […]

July 18, 2017

Published by admin_auro at July 18, 2017

Categories

Cancer
Ideas

Natural product-derived therapy for glioblastoma: Shikonin, isolated from Zicao, inhibits the expression of JMJD6, impairs functioning of transcription elongation machinery, inhibits the proliferation of glioblastoma cells, suppresses tumor cell migration, reduces metastasis and prolongs survival via down regulation of its target gene, 18/July/2017, 10.13 pm

Introduction: What they say: A study from the Department of Stem Cell Biology and Regenerative Medicine, Lerner Research Institute, Ohio, USA shows that “Transcription elongation factors […]

July 17, 2017

Published by admin_auro at July 17, 2017

Categories

Ideas

Vitamin-based therapy for muscle atrophy and wasting: Vitamin-C increases the expression of FGF19 and its receptor ß-Klotho, phosphorylates ERK1/2 and S6K1, decreases the expression of tumor suppressors genes, promotes regeneration of muscle cells and hypertrophy of skeletal muscle, and reverses muscular atrophy and wasting via up regulation of its target gene, 18/July/2017, 1.53 am

Introduction: What they say A study from Department of Biology, University of Bergen, Bergen, Norway; and Univ-Lyon, CarMeN Laboratory, INSERM 1060, INRA 1397, Université Claude Bernard Lyon, INSA Lyon, Oullins, France […]