Ideas

March 13, 2017

Natural product-based therapy for TIIDM and obesity-associated metabolic deficits: Fisetin, a flavanol isolated from strawberries, apples, persimmons, onions, cucumbers, and acacias among others, increases Lipocalin 2 (LCN2) expression, activates an MC4R-dependent anorexigenic pathway, suppresses appetite and weight gain, increases insulin secretion, improves glucose tolerance, promotes glucose homeostasis, improves obesity-associated metabolic deficits and prevents progression to TIIDM via down regulation of its target gene, 13/March/2017, 7.00 am

Introduction: What they say A study from the Department of Physiology-Cellular Biophysics, College of Physicians and Surgeons, Columbia University, New York, New York, USA shows that […]
March 12, 2017

Cardiac rejuvenation therapy: Gambogic acid, derived from Garcinia hanburyi, suppresses tumor suppressor INK4a/p16 expression, inhibits dilated cardiomyopathy and heart failure and extends life span via up regulation of its target gene, 13/March/2017, 12.08 am

Introduction: What they say A recent study from the Stem Cell Aging Group, Centro Nacional de Investigaciones Cardiovasculares, E-28029 Madrid, Spain shows that “Bmi1 limits dilated […]
March 12, 2017

Life-extension therapy: Cardamomin, found in Cardamom and among others, inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span, 12/March/2017, 11.40 pm

What they say?  A study from the Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK shows that “Ribosomal […]
March 12, 2017

Natural product-derived combination therapy for Hepatocellular carcinoma: Hyperoside and Quercetin, isolated from Drosera rotundifolia, and Levisticum officinale, respectively, attenuates phosphoenolpyruvate carboxykinase (PEPCK1) sumoylation, stabilizes PEPCK1 levels, promotes gluconeogenesis, inhibits glycolysis and attenuates the progression of hepatocellular carcinoma via up regulation of its target gene, 12/March/2017, 11.16 pm

Introduction: What they say: A study from the State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen […]
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