Ideas

July 14, 2017

Natural product-based therapy for glucose homeostasis and TIIDM: Celastrol, isolated from Thunder god vine, inhibits Amysin expression, increases insulin secretion, and decreases the risk of hyperglycemia via down regulation of Sox4 and its target gene Amysin, 15/July/2017, 12.26 am

Introduction: What they say Nobel laureate in Physiology/Medicine (1975) Prof. David Baltimore and his research team, from California Institute of Technology, California, USA, had reported in the September 14, 2014 issue of […]
July 14, 2017

Natural product-derived therapy for Stroke: β-Cryptoxanthin, isolated from Sweet peppers, attenuates hippocampal neurons injury, augments regenerative neurogenesis after Ischemic Stroke, and ameliorates stroke damage and neurological deficits via up regulation of its target genes BDNF and NAMPT., 15/July/2017, 12.19 am

Introduction: What they say A recent study from Research Center for Neurobiology and Department of Neurobiology, Xuzhou Medical College, 209 Tongshan Road, Xuzhou, Jiangsu 221004, PR China; and […]
July 14, 2017

Natural product therapy for KRAS/LKB1-mutant lung cancer: Honokiol, isolated from Manolia Grandiflora(MG), increases the levels of tumor suppressor proteins, inhibits the expression of urea cycle enzyme carbamoyl phosphate synthetase-1 (CSP1), decreases pyrimidine pools, stalls DNA synthesis, and inhibits the progression of KRAS/LKB1-mutated lung cancers via up regulation of its target gene, 14/July/2017, 11. 58 pm

Introduction: What they say A study from the Children’s Medical Center Research Institute, UT Southwestern Medical Center, Dallas, Texas 75390, USA; Department of Pediatrics, UT Southwestern Medical Center, […]
July 13, 2017

Natural product-based therapy for Cardiomyopathy: Sulforaphane, isolated from Broccoli, decreases the expression of Sox6, restores the balance between slow- and fast-twitch myofiber proteins and alleviates Cardiomyopathy via up regulation of its target gene, 13/July/2017, 11.10 pm

Introduction: What they say A recent study from the Department of Cardiology, Boston Children’s Hospital, Harvard Medical School, Boston, Massachusetts, USA; and Harvard Stem Cell Institute, Harvard University, Cambridge, Massachusetts, USA shows that “Trbp regulates […]
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