Ideas

July 12, 2017

Hypothermia-based PD-1 pathway activation for Pain therapy: Hypothermia increases the expression of PD-L1, attenuates acutes and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability via up-regulation of its target gen, 13/July/2017, 12.01 am

Introduction:What they say: A recent study from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain Science, Fudan University, Shanghai, […]
July 12, 2017

Natural product derived-therapy for Regenerating the lost pancreatic β-cells in Diabetic patients: Linarin, isolated from Flos Chrysanthemi Indici, increases the expression of IGF1R, INSR, and IRS2, and promotes an insulin-sensitized state via up-regulation of its target gene Lin28, 12/July/2017, 11.55 pm

Introduction: What they say:   A study from the Stem Cell Transplantation Program, Division of Pediatric Hematology/Oncology, Boston Children’s Hospital and Dana-Farber Cancer Institute, Boston, Massachusetts, USA shows that “The Lin28/let-7 axis […]
July 12, 2017

Natural product-derived regenerative therapy for muscle atrophy: Chrysin, isolated from Passiflora caerulea and Passiflora incarnata among others, increases the expression of IGF-1, PI3K(p85a) and B-Myb, decreases the expression of tumor suppressors, promotes regeneration of muscle cells, and reverses muscle atrophy via up regulation of its target gene, 12/July/2017, 11.47 pm

Introduction: What they say A study from the Cardiac Regeneration and Ageing Lab, School of Life Science, Shanghai University, Shanghai 200444, China shows that “miR-29b contributes to multiple types of muscle […]
July 12, 2017

Natural product therapy for glucose homeostasis and TIIDM: Linarin, isolated from Flos Chrysanthemi Indici, increases Pax6 and insulin expression, decreases the levels of glucagon, ghrelin and Somatostatin, reduces metabolic stress, improves insulin sensitivity, promotes glucose homeostasis and prevents progression to TIIDM via down regulation of its target gene, 12/July/2017, 11.39 pm

Introduction: What they say A study from the Department of Developmental Biology and Cancer Research, The Institute for Medical Research Israel-Canada, The Hebrew University-Hadassah Medical School, Jerusalem, […]
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