Ideas

Natural product therapy for Myocardial Infarction: Avicularin, a bio-active flavonol isolated from Polygonum aviculare, Rhododendron aureum and Taxillus kaempferi, improves myocardial function after myocardial infarction via up regulation of PNUTS/PPP1R10 (Serine/threonine-protein phosphatase 1 regulatory subunit 10), 16/October/2016, 7.38 am
Natural product therapy for Myocardial Infarction: Avicularin, a bio-active flavonol isolated from Polygonum aviculare, Rhododendron aureum and Taxillus kaempferi, improves myocardial function after myocardial infarction via up regulation of PNUTS/PPP1R10 (Serine/threonine-protein phosphatase 1 regulatory subunit 10), 16/October/2016, 7.38 am 150 150 Dr Boomi's Genom-2-Discovery Center

A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published in the 7 March  2013 issue of Nature  by Prof Dimmler, Boon, and others. On the foundation of this…

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Natural product Immune enhancement therapy: Hyperoside, found in Drosera Rotundifolia and Prunella vulgaris (Common self-heal), increases SOX2 expression and promotes innate immunity against bacterial infection via down regulation of its target gene, 16/October/2016, 6.17 am
Natural product Immune enhancement therapy: Hyperoside, found in Drosera Rotundifolia and Prunella vulgaris (Common self-heal), increases SOX2 expression and promotes innate immunity against bacterial infection via down regulation of its target gene, 16/October/2016, 6.17 am 150 150 Dr Boomi's Genom-2-Discovery Center

A recent study from the Institute of Biophysics, Chinese Academy of Sciences, Beijing, China shows that “Sox2 functions as a sequence-specific DNA sensor in neutrophils to initiate innate immunity against microbial infection.” This study…

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Natural product anti-inflammatory therapy for upper respiratory tract inflammatory diseases: Ursolic acid, found in apples, increases the expression of negative regulator of inflammation MyD88(s), inhibits pro-inflammatory mediators in lungs, and alleviates the common respiratory pathogen nontypeable Haemophilus influenzae (NTHi)-exacerbated asthma & chronic obstructive pulmonary disease via up-regulation of its target gene, 15/October/2015, 12.22 pm
Natural product anti-inflammatory therapy for upper respiratory tract inflammatory diseases: Ursolic acid, found in apples, increases the expression of negative regulator of inflammation MyD88(s), inhibits pro-inflammatory mediators in lungs, and alleviates the common respiratory pathogen nontypeable Haemophilus influenzae (NTHi)-exacerbated asthma & chronic obstructive pulmonary disease via up-regulation of its target gene, 15/October/2015, 12.22 pm 150 150 Dr Boomi's Genom-2-Discovery Center

A study from the Center for Inflammation, Immunity &Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA, 30303, USA shows that: “Resveratrol suppresses NTHi-induced inflammation via up-regulation of the…

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Molecular therapy for Myocardial Infarction: Sirtuin-7 improves myocardial function after myocardial infarction via up-regulation of PNUTS/PPP1R10 (Serine/threonine-protein phosphatase 1 regulatory subunit 10), 15/October/2016, 11.58 am
Molecular therapy for Myocardial Infarction: Sirtuin-7 improves myocardial function after myocardial infarction via up-regulation of PNUTS/PPP1R10 (Serine/threonine-protein phosphatase 1 regulatory subunit 10), 15/October/2016, 11.58 am 150 150 Dr Boomi's Genom-2-Discovery Center

A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published in the 7 March  2013 issue of Nature  by Prof Dimmler, Boon, and others. On the foundation of this…

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Life-extension therapy: MiR-451 inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span via upregulation of its target genes, 15/October/2016, 9.03 am
Life-extension therapy: MiR-451 inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span via upregulation of its target genes, 15/October/2016, 9.03 am 150 150 Dr Boomi's Genom-2-Discovery Center

A recent study from the Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK shows that “Ribosomal protein S6 kinase 1 signaling regulates…

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Molecular therapy for Metabolic disorders: MiRNA-200a-3p increases (LXR)-α expression, decreases triglyceride and cholesterol levels, increases insulin sensitivity and promotes leanness via down regulation of its target genes, 15/October/2016, 6.50 am
Molecular therapy for Metabolic disorders: MiRNA-200a-3p increases (LXR)-α expression, decreases triglyceride and cholesterol levels, increases insulin sensitivity and promotes leanness via down regulation of its target genes, 15/October/2016, 6.50 am 150 150 Dr Boomi's Genom-2-Discovery Center

Significance:  Given that (1)  more than 387 million people worldwide are affected by Diabetes mellitus (DM); (2) the life-long painful injection/drug treatment required to treat DM; and (3) the global economic…

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