Molecular therapy for Pulmonary Fibrosis: E2F3 increases Toll-like receptor 4 expression and extracellular matrix glycosaminoglycan Hyaluronan levels, promotes alveolar progenitor cell renewal and repair of lung injury and prevents severe pulmonary fibrosis via down regulation of its target gene, 9/October/2015, 10.13 pm

A study from the Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA; and Women’s Guild Lung Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA shows that: “Hyaluronan and TLR4 promote surfactant-protein-C-positive alveolar progenitor cell renewal and prevent severe pulmonary fibrosis in mice.” This study was published in the 03 October 2016 issue of […]

Natural product therapy for Pulmonary Fibrosis: Thermostable extract of fenugreek seeds (TEFS) increases Toll-like receptor 4 expression and extracellular matrix glycosaminoglycan Hyaluronan levels, promotes alveolar progenitor cell renewal and repair of lung injury and prevents severe pulmonary fibrosis via down regulation of its target gene, 9/October/2015, 10.09 pm

A study from the Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA; and Women’s Guild Lung Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA shows that: “Hyaluronan and TLR4 promote surfactant-protein-C-positive alveolar progenitor cell renewal and prevent severe pulmonary fibrosis in mice.” This study was published in the 03 October 2016 issue of […]

Natural product anti-inflammatory therapy for upper respiratory tract inflammatory diseases: Oleanolic acid, one of the main components of Olea europaea and Prosopis glandulosa, increases the expression of negative regulator of inflammation MyD88(s), inhibits pro-inflammatory mediators in lungs, and alleviates the common respiratory pathogen nontypeable Haemophilus influenzae (NTHi)-exacerpated asthma & chronic obstructive pulmonary disease via up regulation of its target gene, 09/October/2015, 6.47 pm

A study from the Center for Inflammation, Immunity &Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA, 30303, USA shows that: “Resveratrol suppresses NTHi-induced inflammation via up-regulation of the negative regulator MyD88 short.” This study was published in the 28 September 2016 issue of the journal “Scientific reports” by Prof. Li JD, Andrews CS […]

Natural product therapy targeting aberrant Lipid synthesis in Human cancers: 8-hydrocalamenene, derived from Reynoutria elliptica, suppresses the expression of the principal enzyme in lipid synthesis, ACLY, inhibits aberrant lipid production in cancer cells and tumor progression via up regulation of its target gene, 8/October/2016, 11.07 pm

A recent study from Rutgers Cancer Institute of New Jersey, Rutgers University, The State University of New Jersey, New Brunswick, New Jersey, USA shows that “Cullin3–KLHL25 ubiquitin ligase targets ACLY for degradation to inhibit lipid synthesis and tumor progression.” This study was published in the 1 September  2016 issue of Genes Development  by Prof Feng Z, Zhang C, and others. On the foundation of this […]

Natural product Life-extension therapy: Ampelopsin (AMP), a flavonol mainly found in Ampelopsis grossedentata, inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span, 8/October/2016, 5.24 pm

A recent study from the Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK shows that “Ribosomal protein S6 kinase 1 signaling regulates mammalian life span.” This study was published in the 2 October 2009 issue of the Journal “Science” (I.F: 31.477 ) by Prof Dominic J. Withers, Dr. Selman C and others. On the foundation of […]

Gaseous therapy for Idiopathic pulmonary fibrosis: Nitric oxide increases TRF1 expression and ameliorates pulmonary fibrosis via upregulation of its target gene, 8/October/2015, 4.54 pm

A study from the Spanish National Cancer Centre, Melchor Fernández Almagro 3, Madrid, Spain“ shows that: “Mice with Pulmonary Fibrosis Driven by Telomere Dysfunction.” This study was published in the 14 July 2015 issue of the journal “Cell Reports” by Prof. Maria, Povedano JM and others. On the foundation of this interesting finding, Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Gaseous therapy for Idiopathic pulmonary fibrosis: […]