Ideas

Natural product therapy for Pulmonary Fibrosis: Onion Peel extract (OPE) increases Toll-like receptor 4 expression and extracellular matrix glycosaminoglycan Hyaluronan levels, promotes alveolar progenitor cell renewal and repair of lung injury and prevents severe pulmonary fibrosis via down regulation of its target gene, 6/October/2015, 1.24 pm
Natural product therapy for Pulmonary Fibrosis: Onion Peel extract (OPE) increases Toll-like receptor 4 expression and extracellular matrix glycosaminoglycan Hyaluronan levels, promotes alveolar progenitor cell renewal and repair of lung injury and prevents severe pulmonary fibrosis via down regulation of its target gene, 6/October/2015, 1.24 pm 150 150 Dr Boomi's Genom-2-Discovery Center

A study from the Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA; and Women’s Guild Lung Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA shows that: “Hyaluronan and…

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Natural product Life-extension therapy: Neem leaf extract inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span via upregulation of its target genes, 6/October/2016, 8.40 am
Natural product Life-extension therapy: Neem leaf extract inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span via upregulation of its target genes, 6/October/2016, 8.40 am 150 150 Dr Boomi's Genom-2-Discovery Center

A recent study from the Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK shows that “Ribosomal protein S6 kinase 1 signaling regulates…

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Life-extension therapy: 3,6-dihydroxyflavone (3,6-DHF) inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span via up regulation of its target gene, 6/October/2016, 7.19 am
Life-extension therapy: 3,6-dihydroxyflavone (3,6-DHF) inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span via up regulation of its target gene, 6/October/2016, 7.19 am 150 150 Dr Boomi's Genom-2-Discovery Center

A recent study from the Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK shows that “Ribosomal protein S6 kinase 1 signaling regulates…

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Natural product Anti-telomerase cancer therapy: Honokiol, a bioactive constituent of Magnolia-grandiflora/dealbata/obovata/officinalis, suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) and inhibits cancer progression via down regulation of its target gene, 5/October/2016, 10.00 am
Natural product Anti-telomerase cancer therapy: Honokiol, a bioactive constituent of Magnolia-grandiflora/dealbata/obovata/officinalis, suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) and inhibits cancer progression via down regulation of its target gene, 5/October/2016, 10.00 am 150 150 Dr Boomi's Genom-2-Discovery Center

The 1989 Nobel prize winner in Chemistry, Prof. Thomas R. Cech from the BioFrontiers Institute, USA has published a research paper in the 13 December 2012 Nature (492(7428):285-9; and I.F: >42) stating that “The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity.”  This study provides mechanistic insights…

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Therapeutic insights into “awakening the sleeping angel” in mutant p53-expressing human tumors: MiR-497 increases the expression of tumor suppressor p53 homologue TAp63γ and induces regression of p53-mutated human tumors via down regulation of its target gene, 5/October/2016, 8.14 am
Therapeutic insights into “awakening the sleeping angel” in mutant p53-expressing human tumors: MiR-497 increases the expression of tumor suppressor p53 homologue TAp63γ and induces regression of p53-mutated human tumors via down regulation of its target gene, 5/October/2016, 8.14 am 150 150 Dr Boomi's Genom-2-Discovery Center

Significance: Cancer suppressor p53 is mutated in more than 50% of human cancers of different origin, while its pathway is altered in about 80% of tumors. This study suggests a…

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Molecular therapy for Myocardial Infarction: JunB improves myocardial function after myocardial infarction via up regulation of PNUTS/PPP1R10 (Serine/threonine-protein phosphatase 1 regulatory subunit 10), 5/October/2016, 7.38 am
Molecular therapy for Myocardial Infarction: JunB improves myocardial function after myocardial infarction via up regulation of PNUTS/PPP1R10 (Serine/threonine-protein phosphatase 1 regulatory subunit 10), 5/October/2016, 7.38 am 150 150 Dr Boomi's Genom-2-Discovery Center

A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published in the 7 March  2013 issue of Nature  by Prof Dimmler, Boon, and others. On the foundation of this…

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