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Pain

September 18, 2018

Mechanistic insights into how a known anesthetic drug functions as an analgesic agent: Levobupivacaine (brand name: Chirocaine),  a local anesthetic drug, increases the expression of PD-L1, attenuates acute and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability, via up-regulation of its target gene, 18/September/2018, 7.56 am

Introduction: What they say: A recent study from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for […]
September 18, 2018

A new mechanistic insight into a known heart failure medicine in Pain therapy: Dobutamine (brand name: dobutrex, inotrex), used in the treatment of congestive heart failure and cardiogenic shock,  increases the expression of PD-L1, attenuates acute and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability, via up-regulation of its target gene, 18/September/2018, 6.24 am

Introduction: What they say: A recent study from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for […]
September 14, 2018

Probiotics-based induction of the PD-1 pathway for Pain therapy: Probiotics  increase the expression of PD-L1, attenuate acute and chronic pain, and suppress mechanical and thermal hypersensitivity and inhibit nociceptive neuron excitability, via up-regulation of its target gene, 14/September/2018, 10.38 pm

Introduction: What they say: A recent study from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for […]
September 14, 2018

Induction of the PD-1 pathway for Pain therapy: Thiopental (brand name: Pentothal), a general anesthetic,  increases the expression of PD-L1, attenuates acute and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability via up-regulation of its target gene, 14/September/2018, 8.27 pm

Introduction:What they say: A recent study from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain […]