Pain

April 21, 2018

Bonding your way to lead a pain-free life: Oxytocin-based activation of the PD-1 pathway for Pain therapy: Oxytocin (also known as compassion/goodness/bonding hormone), a peptide hormone and neuropeptide known to play a role in empathy, generosity, childbirth and so on, increases the expression of PD-L1, attenuates acutes and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability via up-regulation of its target gene, 21/April/2018, 7.07 am

Introduction:What they say: A recent study, from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain […]
April 14, 2018

Treating pain with Endorphins: Endorphin-based activation of the PD-1 pathway for Pain therapy: β-Endorphin, an endogenous opioid neuropeptide and peptide hormone known to play a role in hunger, thrill, pain, maternal care, reward, and cognition, increases the expression of PD-L1, attenuates acutes and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability via up-regulation of its target gene, 14/April/2018, 11.47 pm

Introduction:What they say: A recent study, from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain […]
April 9, 2018

An omega-3 way to treat pain:  PUFA-based activation of the PD-1 pathway for Pain therapy:  ω-PUFAs (Docosahexaenoic acid (DHA) + Eicosapentaenoic acid (EPA) increase the expression of PD-L1, attenuate acutes and chronic pain, suppress mechanical and thermal hypersensitivity and inhibit nociceptive neuron excitability, via up-regulation of its target gene, 9/April/2018, 6.31 am

Introduction:What they say: A recent study from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain […]
March 31, 2018

A sweet way to treat pain: Trisaccharide-based activation of the PD-1 pathway for Pain therapy: Raffinose, a trisaccharide composed of galactose, glucose, and fructose, increases the expression of PD-L1, attenuates acutes and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability via up-regulation of its target gene, 31/March/2018, 10.57 pm

Introduction:What they say: A recent study, from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain […]