Pain

March 31, 2018

A sweet way to treat pain: Trisaccharide-based activation of the PD-1 pathway for Pain therapy: Raffinose, a trisaccharide composed of galactose, glucose, and fructose, increases the expression of PD-L1, attenuates acutes and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability via up-regulation of its target gene, 31/March/2018, 10.57 pm

Introduction:What they say: A recent study, from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain […]
March 16, 2018

A sweet way to say no to pain: Sugar-based PD-1 pathway activation for Pain therapy: Phyllodulcin, a natural sweetener 400-800 times sweeter than sugar, increases the expression of PD-L1, attenuates acutes and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability, via up-regulation of its target gene, 16/March/2017, 7.40 am

Introduction:What they say: A recent study from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain […]
March 4, 2018

Activation of the PD-1 pathway for Pain therapy: DAMGO ([D-Ala2, N-MePhe4, Gly-ol]-enkephalin), a synthetic opioid peptide, increases the expression of PD-L1, attenuates acutes and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability via up-regulation of its target gene, 4/March/2017, 11.07 am

Introduction:What they say: A recent study, from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain […]
March 1, 2018

Activation of the PD-1 pathway for Pain therapy: DADLE ([D-Ala2, D-Leu5]-Enkephalin), a synthetic opioid peptide, increases the expression of PD-L1, attenuates acutes and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability via up-regulation of its target gene, 1/March/2017, 10.56 pm

Introduction:What they say: A recent study, from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain […]