Pain

Solving a sixty plus year puzzle as to how Bupivacaine functions as a pain reliever: Mechanistic insights into how Bupivacaine functions as a local anesthetic agent: Bupivacaine  (trade name: Marcaine, Sensorcaine, Vivacaine, others ), used to decrease feeling in a specific area of the body, in post-operative pain management, in the treatment of lower back pain and in others,  increases the expression of PD-L1, decreases the expression of Cox-2, TRPV1, and CGPR, attenuates acutes and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability, via up-regulation of its target gene, 24/July/2019, 6.34 am

Solving a sixty plus year puzzle as to how Bupivacaine functions as a pain reliever: Mechanistic insights into how Bupivacaine functions as a local anesthetic agent: Bupivacaine  (trade name: Marcaine, Sensorcaine, Vivacaine, others ), used to decrease feeling in a specific area of the body, in post-operative pain management, in the treatment of lower back pain and in others,  increases the expression of PD-L1, decreases the expression of Cox-2, TRPV1, and CGPR, attenuates acutes and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability, via up-regulation of its target gene, 24/July/2019, 6.34 am 1280 720 Dr Boomi's Genom-2-Discovery Center

Introduction:What they say: A recent study from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain Science, Fudan University, Shanghai,…

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Solving a sixty-year old puzzle as to how Amitriptyline functions as a pain reliever: Mechanistic insights into how Amitriptyline functions as a pain medication: Amitriptyline (trade name: Elatrol, Elatrolet, Elavil, Endep, Fiorda, Laroxyl, Latilin, Levate and others), used in the treatment for major depressive order, and anxiety disorders, prevention of migraines, fibromyalgia, postherpetic neuralgia, and insomnia,  increases the expression of PD-L1, decreases the expression of Cox-2, TRPV1, and CGPR, attenuates acutes and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability, via up-regulation of its target gene, 12/July/2019, 11.29 pm

Solving a sixty-year old puzzle as to how Amitriptyline functions as a pain reliever: Mechanistic insights into how Amitriptyline functions as a pain medication: Amitriptyline (trade name: Elatrol, Elatrolet, Elavil, Endep, Fiorda, Laroxyl, Latilin, Levate and others), used in the treatment for major depressive order, and anxiety disorders, prevention of migraines, fibromyalgia, postherpetic neuralgia, and insomnia,  increases the expression of PD-L1, decreases the expression of Cox-2, TRPV1, and CGPR, attenuates acutes and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability, via up-regulation of its target gene, 12/July/2019, 11.29 pm 1280 720 Dr Boomi's Genom-2-Discovery Center

Introduction:What they say: A recent study from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain Science, Fudan University, Shanghai,…

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Probiotics as Analgesics: Probiotic bifidobacterium animalis subsp. lactus LKM512  functions as a pain reliever: Mechanistic insights into how Probiotic bifidobacterium animalis subsp. lactus LKM512  functions as a pain medication: Probiotic bifidobacterium animalis subsp. lactus LKM512  increases the expression of PD-L1, TRPV1, and CGPR, decreases the expression of Cox-2, attenuates acutes and chronic pain, headache, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability, via up-regulation of its target gene, 17/July/2019, 11.51 am

Probiotics as Analgesics: Probiotic bifidobacterium animalis subsp. lactus LKM512  functions as a pain reliever: Mechanistic insights into how Probiotic bifidobacterium animalis subsp. lactus LKM512  functions as a pain medication: Probiotic bifidobacterium animalis subsp. lactus LKM512  increases the expression of PD-L1, TRPV1, and CGPR, decreases the expression of Cox-2, attenuates acutes and chronic pain, headache, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability, via up-regulation of its target gene, 17/July/2019, 11.51 am 1280 720 Dr Boomi's Genom-2-Discovery Center

Introduction:What they say: A recent study from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain Science, Fudan University, Shanghai,…

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Solving a long standing puzzle as to how Astragalus membranaceus functions as a pain reliever: Mechanistic insights into how Astragalus membranaceus-derived compound Astragaloside  functions as a pain medication: Astragaloside, derived from Astragalus membranaceus or its oil,  increases the expression of PD-L1, TRPV1, and CGPR, decreases the expression of Cox-2, attenuates acutes and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability, via up-regulation of its target gene, 12/July/2019, 11.39 pm

Solving a long standing puzzle as to how Astragalus membranaceus functions as a pain reliever: Mechanistic insights into how Astragalus membranaceus-derived compound Astragaloside  functions as a pain medication: Astragaloside, derived from Astragalus membranaceus or its oil,  increases the expression of PD-L1, TRPV1, and CGPR, decreases the expression of Cox-2, attenuates acutes and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability, via up-regulation of its target gene, 12/July/2019, 11.39 pm 1280 720 Dr Boomi's Genom-2-Discovery Center

Introduction:What they say: A recent study from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain Science, Fudan University, Shanghai,…

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Solving a century-old puzzle as to how Turmeric functions as a pain reliever: Mechanistic insights into how Turmeric-derived compound Curcumin functions as a pain medication: Curcumin, derived from turmeric or its oil,  increases the expression of PD-L1, decreases the expression of Cox-2, attenuates acutes and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability, via up-regulation of its target gene, 12/July/2019, 11.27 pm

Solving a century-old puzzle as to how Turmeric functions as a pain reliever: Mechanistic insights into how Turmeric-derived compound Curcumin functions as a pain medication: Curcumin, derived from turmeric or its oil,  increases the expression of PD-L1, decreases the expression of Cox-2, attenuates acutes and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability, via up-regulation of its target gene, 12/July/2019, 11.27 pm 1280 720 Dr Boomi's Genom-2-Discovery Center

Introduction:What they say: A recent study from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain Science, Fudan University, Shanghai,…

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Mechanistic insights into how Methylprednisolone(MPD) may function as a pain medication: Methylprednisolone(MPD),  used in the treatment of rheumatic disorders, asthma, allergies and others,  increases the expression of PD-L1, decreases the expression of Cox-2, attenuates acutes and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability, via up-regulation of its target gene, 12/July/2019, 10.26 pm

Mechanistic insights into how Methylprednisolone(MPD) may function as a pain medication: Methylprednisolone(MPD),  used in the treatment of rheumatic disorders, asthma, allergies and others,  increases the expression of PD-L1, decreases the expression of Cox-2, attenuates acutes and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability, via up-regulation of its target gene, 12/July/2019, 10.26 pm 1280 720 Dr Boomi's Genom-2-Discovery Center

Introduction:What they say: A recent study from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain Science, Fudan University, Shanghai,…

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