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Tuberculosis

April 7, 2018

Steroid-based therapy for tuberculosis: 17-β estradiol, a steroid hormone, deacetylates RelA/p65, inhibits inflammatory gene expression downstream of RelA/p65, inhibits TB pathogenesis, increases the efficacy of anti-TB drug, and promotes M. tuberculosis clearance via up regulation of its target gene, 7/April/2018, 10.54 pm

Introduction: What they say: A study from the Singapore Immunology Network, Agency for Science, Technology and Research, Singapore; and Lee Kong Chian School of Medicine, Nanyang […]
March 18, 2018

Sugar-based therapy for tuberculosis: Lactulose, a non-absorbable sugar used in the treatment of constipation and hepatic encephalopathy, deacetylates RelA/p65, inhibits inflammatory gene expression downstream of RelA/p65, inhibits TB pathogenesis, increases the efficacy of anti-TB drug, and promotes M. tuberculosis clearance via up regulation of its target gene, 18/March/2018, 11.24 am

Introduction: What they say: A study from the Singapore Immunology Network, Agency for Science, Technology and Research, Singapore; and Lee Kong Chian School of Medicine, Nanyang […]
March 3, 2018

Molecular therapy for tuberculosis: Carvedilol (brand name: Coreg), used in treatment of congestive heart failure and left ventricular dysfunction, deacetylates RelA/p65, inhibits inflammatory gene expression downstream of RelA/p65, inhibits TB pathogenesis, increases the efficacy of anti-TB drug, and promotes M. tuberculosis clearance via up regulation of its target gene, 3/March/2018, 9.23 am

Introduction: What they say: A study from the Singapore Immunology Network, Agency for Science, Technology and Research, Singapore; and Lee Kong Chian School of Medicine, Nanyang […]
March 2, 2018

Molecular therapy for tuberculosis: Triclosan, an antibacterial and antifungal agent found commonly in toothpastes, soaps, among others, deacetylates RelA/p65, inhibits inflammatory gene expression downstream of RelA/p65, inhibits TB pathogenesis, increases the efficacy of anti-TB drug, and promotes M. tuberculosis clearance via up regulation of its target gene, 2/March/2018, 8.06 am

Introduction: What they say: A study from the Singapore Immunology Network, Agency for Science, Technology and Research, Singapore; and Lee Kong Chian School of Medicine, Nanyang […]