Molecular therapy for tuberculosis (TB): Clioquinol[iodochlorhydroxyquin] (Trade name:Cortin), an antifungal and antiprotozoal drug that inhibits certain enzymes related to DNA replication, deacetylates RelA/p65, inhibits inflammatory gene expression downstream of RelA/p65, inhibits TB pathogenesis, increases the efficacy of anti-TB drug, and promotes M. tuberculosis clearance via upregulation of its target gene, 28/March/2019, 5.47 am
Molecular therapy for tuberculosis (TB): Clioquinol[iodochlorhydroxyquin] (Trade name:Cortin), an antifungal and antiprotozoal drug that inhibits certain enzymes related to DNA replication, deacetylates RelA/p65, inhibits inflammatory gene expression downstream of RelA/p65, inhibits TB pathogenesis, increases the efficacy of anti-TB drug, and promotes M. tuberculosis clearance via upregulation of its target gene, 28/March/2019, 5.47 am
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