Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
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Citation: Boominathan, MiRNA-based therapy for Life span extension: Pro-proliferative gene c-Myc inhibits senescence and exends life span by down regulating the expression of ADCY5, 2/September/2014, 12.33 pm, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
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Significance: This study suggests that c-Myc extends life-span by suppressing the expression of ADCY5, while increasing the expression of longevity-associated genes such as telomerase and Siruin-1. Thus, pharmacological formulations encompassing “c-Myc activator” may be used to inhibit ageing process and extend life-span.