Research findings to Therapeutic opportunity:
The study presented here suggests that (6)-gingerol (6G), by increasing the expression of its target genes, it may increase the expression of Tissue inhibitor of metalloproteinases 3 (TIMP3). Thereby, it may inhibit migration, invasion and metastasis of cancer cells. Thus, pharmacological formulations encompassing “(6)-gingerol (6G) or its analogues” may be used to inhibit the progression of invasive tumors.
Details of the research findings:
Idea Proposed/Formulated (with experimental evidence) by:
Dr L Boominathan Ph.D.
Undisclosed information: How (6)-gingerol (6G) increases the expression of metastasis suppressor Tissue inhibitor of metalloproteinases 3 (TIMP3)
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References:
Citation: Boominathan, L., Natural product-based therapy for Metastatic cancers: (6)-gingerol (6G), one of the main components of Ginger, increases the expression of Tissue inhibitor of metalloproteinases 3 (TIMP3) and inhibits migration, invasion and metastasis of cancer cells via down regulation of its target gene, 19/February/2017, 2.26 pm, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
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