A study from Karolinska Institutet, Stockholm, Sweden shows that “MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool.”
This study was published in the April 10, 2014 Nature [I.F >42] by Prof. Thomas H, Dr Gad H and others from Science for Life Laboratory, Division of Translational Medicine and Chemical Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.
On the foundation of this interesting finding, Dr L Boominathan, Director-cum-Chief-Scientist of GBMD, reports here that: Natural product-based cancer therapy: Neem leaf extract inhibits cancer development by suppressing the expression of nucleotide sanitizing enzyme MTH1/NUDT1.
Significance:
This study suggests that Neem leaf extract, by up-regulating its target gene, it may suppress the expression of MTH1/NUDT1. Thus, pharmacological formulations encompassing “Neem leaf extract or an active compound isolated from it” may be used in the treatment of human cancers.
Neem leaf extract inhibits human cancer development via down-regulation of MTH1/NUDT1
Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
Web: http://genomediscovery.org or http://newbioideas.com
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Undisclosed information: How Neem leaf extract suppresses the expression of MTH1/NUDT1
Results guaranteed if not refunded
To cite: Boominathan, Natural product cancer therapy: Neem leaf extract inhibits cancer development by suppressing the expression of nucleotide sanitizing enzyme MTH1/NUDT1 via up-regulation of its target gene, 6/October/2016, 2.29 pm, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
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# Research cooperation