Repurposing the anti-epileptic drug Valproic acid into an anti-diabetic (autoimmune) drug: Valproic acid (brand name: Convulex, Depakote, Epilim, Stavzor), a medication used to treat epilepsy and bipolar disorder and to prevent migraine headaches, increases PD-L1 expression, increases Tregs function, promotes immune tolerance, increases pancreatic β-cell proliferation and regeneration, increases insulin secretion, improves insulin sensitivity, increases energy utilization, and reverses TIDM, via up-regulation of its target gene, 13/november/2018, 11.59 pm
Repurposing the anti-epileptic drug Valproic acid into an anti-diabetic (autoimmune) drug: Valproic acid (brand name: Convulex, Depakote, Epilim, Stavzor), a medication used to treat epilepsy and bipolar disorder and to prevent migraine headaches, increases PD-L1 expression, increases Tregs function, promotes immune tolerance, increases pancreatic β-cell proliferation and regeneration, increases insulin secretion, improves insulin sensitivity, increases energy utilization, and reverses TIDM, via up-regulation of its target gene, 13/november/2018, 11.59 pm
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