Stalling arthritic pain with statins: Statin-based therapy for inflammation and arthritis:Lovastatin, an inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA reductase) which is used to reduce cholesterol levels and treat dyslipidemia, increases IL-9 levels, augments proliferation of ILC2s (type 2 innate lymphoid cells) and regulatory T (Treg) cells, promotes resolution of inflammation, attenuates cartilage destruction, decreases bone loss, and inhibits pathological features associated with arthritis via up-regulation of its target genes, 29/March/2018, 9.08 am