An elavil-way to extend lifespan and healthspan: Amitriptyline (trade name: Elavil), used in the treatment of major depressive disorder, anxiety disorder, migraines, neuropathic pain, and others, inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span via up regulation of its target gene, 16/April/2017, 9.55 am