Ideas – Page 101

March 26, 2019

Published by admin_auro at March 26, 2019

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Intracardiac injection of Erythropoietin/Hematopoietin protects against cardiac hypertrophy and fibrosis: Intracardiac injection of erythropoietin/hematopoietin decreases MiR-29 expression, activates wnt- signaling and its components GSK3B, ICAT/CTNNBIP1, HBP1, and GLIS2, attenuates pathologic hypertrophy, inhibits fibrosis of the heart tissue, and improves cardiac function via upregulation of its target gene, 26/March/2019, 11.13 pm

Introduction: What they say: A recent study from the Institute of Pharmacology and Toxicology, Technical University Munich (TUM), 80802, Munich, Germany; DZHK (German Center for Cardiovascular […]

March 26, 2019

Published by admin_auro at March 26, 2019

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Repurposing the antibiotic Enoxacin into a broad-spectrum anti-infective agent: Enoxacin (Trade names: Comprecin, Enoksetin, Enoxen, Enroxil, Enoxin, Enoxor, Flumark and others), a fluoroquinolone-based antibiotic commonly used in the treatment of urinary tract infections and gonorrhea, inhibits Hepatitis-B/C, Dengue, Zika, Ebola, HIV-1, Mtb, Malaria, CMV, Influenza H1NI1, respiratory syncytial, Sindbis, and SFV viruses by increasing the Levels of the Antiviral Proteins IFITM3, & Interferon-stimulated gene 15, 26/March/2019, 10.38 pm

Introduction: What they say: A study from the Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard Medical School, Charlestown, MA 02129, USA […]

March 26, 2019

Published by admin_auro at March 26, 2019

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A sweet way to stay free of cardiac diseases: Sugar-based Regenerative therapy for regaining the lost cardiomyocytes in Myocardial patients: Trehalose, an artificial sweetener composed of two glucose molecules, increases the expression of ERBB2/Her2 and promotes dedifferentiation of cardiomyocytes, via up-regulation of its target gene, 26/March/2018, 10.29 pm

Introduction: What they say A recent study from the Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel shows that “ERBB2 triggers mammalian heart regeneration by promoting cardiomyocyte dedifferentiation and proliferation.” This study was […]

March 25, 2019

Published by admin_auro at March 25, 2019

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Molecular Hydrogen gas-based therapy for heart regeneration and repair: Intracardiac or subcutaneous injection of Hydrogen gas decreases tumor suppressor MiR-128 and cyclin-dependent kinase inhibitor p27 expression, increases SUZ12 expression, increases Cyclin E and CDK2 expression, promotes proliferation/re-entry of postnatal/adult cardiomyocytes, attenuates fibrosis, ameliorates cardiac dysfunction, and promotes heart repair in response to myocardial infarction, via up-regulation of its target gene, 25/March/2019, 2.18 pm

Introduction: What they say: A recent study from Department of Pathology and Laboratory Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, 45267, USA; Key Laboratory […]