Ideas

September 5, 2018

Published by admin_auro at September 5, 2018

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Consuming one dark chocolate bar a day strengthen your heart: Dark chocolate-based therapy for cardiomyocyte proliferation and heart regeneration: Dark chocolate decreases tumor suppressor Mir-128 and cyclin-dependent kinase inhibitor p27 expression, increases SUZ12 expression, increases Cyclin E and CDK2 expression, promotes proliferation/re-entry of postnatal/adult cardiomyocytes, attenuates fibrosis, ameliorates cardiac dysfunction, and promotes heart repair in response to myocardial infarction, via up-regulation of its target gene, 5/September/2018, 10.30am

Teacher’s day special ********* We wish everyone a happy Teacher’s day. On this special occasion, we are happy to announce that ideas posted today (05/September/2017) will be available to […]

September 5, 2018

Published by admin_auro at September 5, 2018

Categories

Ideas
Stroke

Eating one chocolate bar a day keeps stroke at bay: Chocolate-based therapy for Stroke: Theobromine, one of the components of dark chocolate, attenuates hippocampal neurons injury, augments regenerative neurogenesis after Ischemic Stroke, and ameliorates stroke damage and neurological deficits, via up-regulation of its target genes BDNF and NAMPT, 5/September/2018, 9.24 am

Teacher’s day special ********* We wish everyone a happy Teacher’s day. On this special occasion, we are happy to announce that ideas posted today (05/September/2017) will be available to […]

September 3, 2018

Published by admin_auro at September 3, 2018

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Cancer
Ideas

Act(os) against cancer: Pioglitazone (trade name: Actos), an anti-diabetic drug, increases the expression of tumor suppressors genes, such as CADM1, RECK, p53, TAp63, TAp73, INK4a/ARF, and others, induces regression of p53-mutated human tumors, via down-regulation of its target gene, 4/September/2018, 1.50 am

From Significance of the study to Public health relevance: Given that: (1) cancer suppressor p53 is mutated in more than 50% of human cancers of different […]

September 3, 2018

Published by admin_auro at September 3, 2018

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Regular dark chocolate consumption may insulate your heart against cardiac dysfunction: Chocolate-derived compound theobromine-based adjunct therapy for cardiac hypertrophy and fibrosis: Theobromine, one of the main components of dark chocolate, decreases Mir-29 expression, activates Wnt- signaling and its components GSK3B, ICAT/CTNNBIP1, HBP1, and GLIS2, attenuates pathologic hypertrophy, inhibits fibrosis of the heart tissue, and improves cardiac function via upregulation of its target gene, 4/September/2018, 1.42 am

Introduction: What they say: A recent study from the Institute of Pharmacology and Toxicology, Technical University Munich (TUM), 80802, Munich, Germany; DZHK (German Center for Cardiovascular […]