Ideas

August 21, 2017

Natural product-derived therapy for tuberculosis: N-Acetylcysteine (NAC) deacetylates RelA/p65, inhibits inflammatory gene expression downstream of RelA/p65, inhibits TB pathogenesis, increases the efficacy of anti-TB drug, and promotes M. tuberculosis clearance via up regulation of its target gene, 22/August/2017, 1.28 am

Introduction: What they say: A study from the Singapore Immunology Network, Agency for Science, Technology and Research, Singapore; and Lee Kong Chian School of Medicine, Nanyang […]
August 21, 2017

Natural product-based therapy for anxiety and depression: Dihydromyricetin (DHM), a natural flavonoid derived from Ampeopsis Grossdentatam, decreases PHF8 levels, increases the expression of serotonin receptors Htr1a and Htr2a, and promotes resistance to stress-induced -anxiety and -depression via down regulation of its target gene, 22/August/2017, 12.54 am

Introduction: What they say: A study from Department of Molecular Biology, Cancer Center and Center for Regenerative Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA; Department […]
August 21, 2017

Natural product-derived therapy for gynecologic cancers: A therapeutic mix encompassing N-Acetylcysteine, Capsaicin, and Sulforaphane (NCS) inhibits the expression of HDAC6, acetylates tumor suppressor proteins, activates tumor suppressor function, and stifles the progression of ARID1A-mutated ovarian cancers via up-regulation of its target gene, 21/August/2017, 11.58 am

Introduction: What they say: A study from Gene Expression and Regulation Program, The Wistar Institute, Philadelphia, Pennsylvania 19104, USA shows that “ARID1A-mutated ovarian cancers depend on […]
August 21, 2017

Natural product-derived Combinatorial therapy targeting CMTM6/4-PD-L1 pathway enhances the efficacy of Cancer immunotherapy: A therapeutic mix encompassing Artemisinin , Capsaicin and Kaempferol, inhibits the expression of transmembrane protein CMTM6/CMTM4, increases interferon-IFNγ signalling, augments antigen presentation and unfolding response, increases Cytotoxic activity of T-cells, decreases tumor burden and increases survival via up-regulation of its target gene, 21/August/2017, 11.41 pm

Introduction:What they say: A recent study from Division of Molecular Oncology & Immunology, The Netherlands Cancer Institute, Plesmanlaan, CX Amsterdam, The Netherlands has identified CMTM6 and […]
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