Ideas

Natural product-derived therapy for Myocardial Infarction: Tyrosol, found in Olive oil and argan oil among others, inhibits DNA damage responses, induces telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction via up-regulation of PNUTS, 16/January/2017, 11.59 pm
Natural product-derived therapy for Myocardial Infarction: Tyrosol, found in Olive oil and argan oil among others, inhibits DNA damage responses, induces telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction via up-regulation of PNUTS, 16/January/2017, 11.59 pm 150 150 Dr Boomi's Genom-2-Discovery Center

What they say:  A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published in the 7 March  2013 issue of Nature  by Prof Dimmler, Boon, and others. What we…

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Natural product-derived therapy for Human Leukemias: Manumycin A, an antibiotic that acts as an inhibitor of farnesyltransferase (FTase), suppresses B-Cell and myeloid leukemias via up regulation of the tumor suppressor IRF4, 16/January/2016, 11.45 pm
Natural product-derived therapy for Human Leukemias: Manumycin A, an antibiotic that acts as an inhibitor of farnesyltransferase (FTase), suppresses B-Cell and myeloid leukemias via up regulation of the tumor suppressor IRF4, 16/January/2016, 11.45 pm 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say Noble laureate in Physiology/Medicine (1975) Prof. David Baltimore, from California Institute of Technology, California, USA, had reported in the July 8, 2014 issue of the Journal “Blood” that: “Dual mechanisms by which MiR-125b represses IRF4 to…

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Fish oil therapy for glucose homeostasis and TIIDM: Docosahexaenoic acid (DHA), found in fish oil and algae oil among others, increases Pax6 and insulin expression, decreases the levels of glucagon, ghrelin and Somatostatin, reduces metabolic stress, improves insulin sensitivity, promotes glucose homeostasis and prevents progression to TIIDM via down regulation of its target gene, 16/January/2017, 11.21 pm
Fish oil therapy for glucose homeostasis and TIIDM: Docosahexaenoic acid (DHA), found in fish oil and algae oil among others, increases Pax6 and insulin expression, decreases the levels of glucagon, ghrelin and Somatostatin, reduces metabolic stress, improves insulin sensitivity, promotes glucose homeostasis and prevents progression to TIIDM via down regulation of its target gene, 16/January/2017, 11.21 pm 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Department of Developmental Biology and Cancer Research, The Institute for Medical Research Israel-Canada, The Hebrew University-Hadassah Medical School, Jerusalem, Israel shows that…

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Natural product-derived therapy for Metastatic human tumors: β-Asarone (1-propenyl-2,4,5-methoxybenzol), found in herb Acorus calamus Linn, inhibits the expression of a number of enzymes in glycolytic cycle, and suppresses proliferation, migration, invasion, tumorigenesis and metastasis via up regulation of its target gene, 16/January/2017, 10.50 pm
Natural product-derived therapy for Metastatic human tumors: β-Asarone (1-propenyl-2,4,5-methoxybenzol), found in herb Acorus calamus Linn, inhibits the expression of a number of enzymes in glycolytic cycle, and suppresses proliferation, migration, invasion, tumorigenesis and metastasis via up regulation of its target gene, 16/January/2017, 10.50 pm 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say: A study from the State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, Fujian 361102,…

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Anticancer therapy targeting the cancer stem cells: MiRNA-9600 inhibits the expression of stem cell gene/reprogramming protein Sox2, suppresses proliferation, and promotes apoptosis of cancer cells via down regulation of its target gene, 16/January/2016, 10.14 pm
Anticancer therapy targeting the cancer stem cells: MiRNA-9600 inhibits the expression of stem cell gene/reprogramming protein Sox2, suppresses proliferation, and promotes apoptosis of cancer cells via down regulation of its target gene, 16/January/2016, 10.14 pm 150 150 Dr Boomi's Genom-2-Discovery Center

Research findings to Therapeutic opportunity:   The study presented here suggests that MiRNA-9600, by increasing the expression of its target genes, it may decrease the expression of the protein that is enriched in cancer…

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Natural product-based Lifespan extension therapy: Marrubium vulgare extract activates autophagy and extends lifespan via up regulation of ATG5, 15/January/2017, 11.41 pm
Natural product-based Lifespan extension therapy: Marrubium vulgare extract activates autophagy and extends lifespan via up regulation of ATG5, 15/January/2017, 11.41 pm 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Global Research Laboratory, Seoul National University, Korea shows that “Overexpression of Atg5 in mice activates autophagy and extends lifespan.” This study was published in the online…

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