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Ideas

March 24, 2017

Natural product-derived therapy for glucose homeostasis and TIIDM: Berberine, found in Berberis, Berberis aristata, Hydrastis canadensis, Phellodendron amurense, and Argemone mexicana among others, increases Barr2 expression, augments the functional activity of CAMKII, increases insulin secretion, promotes glucose homeostasis, prevents progression to TIIDM and ameliorates obesity-associated metabolic deficits via down regulation of its target gene, 24/March/2017, 10.53 pm

Introduction: What they say A study from the Molecular Signaling Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland […]
March 24, 2017

Natural product-derived Lifespan extension therapy: Berberine, found in Berberis, Berberis aristata, Hydrastis canadensis, Phellodendron amurense, and Argemone mexicana, among others, prolongs mammalian life span via down regulation of angiotensin II type I receptor (AT1R), 24/March/2017, 7.00 pm

Significance of the study: It has been shown earlier that antagonizing angiotensin II type I receptor (AT1R) expression may prolong mammalian life span. Further, it has been shown […]
March 24, 2017

Natural product-derived therapy for Human cancers: Shikonin, one of the main components of herb Zicao, increases the expression of mitochondrial protein LACTB, decreases levels of mitochondrial phosphatidylserine decarboxylase, alters mitochondrial lipid metabolism, and promotes differentiation of breast cancer cells via up-regulation of its target gene, 24/March/2017, 6.37 pm

Introduction: What they say: A study from the Whitehead Institute for Biomedical Research, 9 Cambridge Center, Cambridge, Massachusetts, USA Department of Biology, Massachusetts Institute of Technology, […]
March 24, 2017

Natural product-derived Combination therapy for Squamous cell carcinoma of head and neck (HNSCC): A therapeutic mix encompassing an anticancer drug, 1,25-dihydroxyvitamin D and Luteolin may inhibit BMI1 and AP-1 expression, overcome chemotherapeutic resistance, promote chemosensitivity, suppress cancer stem cells in HNSCC, and inhibit lymph node metastasis via down regulation of its target genes , 24/March/2017, 6.04 pm

Introduction: What they say: A study from the Laboratory of Molecular Signaling, Division of Oral Biology and Medicine, Jonsson Comprehensive Cancer Center and Broad Stem Cell Research […]
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