Ideas

Immune enhancement therapy: Lithium increases SOX2 expression and promotes innate immunity against bacterial infection via down-regulation of its target gene, 21/December/2016, 10.43 pm
Immune enhancement therapy: Lithium increases SOX2 expression and promotes innate immunity against bacterial infection via down-regulation of its target gene, 21/December/2016, 10.43 pm 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say: A recent study from the Institute of Biophysics, Chinese Academy of Sciences, Beijing, China shows that “Sox2 functions as a sequence-specific DNA sensor in neutrophils to initiate innate immunity…

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Natural product-derived therapy for Bone disorders: Matrine, found in herb Sophora flavescens, inhibits the expression of Tgif2 and suppresses osteoporosis and bone metastasis via up-regulation of its target gene, 21/December/2016, 6.20 pm
Natural product-derived therapy for Bone disorders: Matrine, found in herb Sophora flavescens, inhibits the expression of Tgif2 and suppresses osteoporosis and bone metastasis via up-regulation of its target gene, 21/December/2016, 6.20 pm 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say:  A study from the Department of Pharmacology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA has reported that “miR-34a blocks osteoporosis and bone metastasis by inhibiting osteoclastogenesis…

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Molecular therapy for Myocardial Infarction: PDLIM1/2 (PDZ And LIM Domain 1) inhibit DNA damage responses, increase telomerase expression, inhibit telomere shortening, and promote cardiomyocyte survival after myocardial infarction via up-regulation of PNUTS, 21/December/2016, 2.46 pm
Molecular therapy for Myocardial Infarction: PDLIM1/2 (PDZ And LIM Domain 1) inhibit DNA damage responses, increase telomerase expression, inhibit telomere shortening, and promote cardiomyocyte survival after myocardial infarction via up-regulation of PNUTS, 21/December/2016, 2.46 pm 150 150 Dr Boomi's Genom-2-Discovery Center

What they say:  A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published in the 7 March  2013 issue of Nature  by Prof Dimmler, Boon, and others. What we…

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Natural product-derived therapy for Human Leukemias: Shikonin, found in Zicao (also known as purple gromwell), suppresses B-Cell and myeloid leukemias via up regulation of the tumor suppressor IRF4, 20/December/2016
Natural product-derived therapy for Human Leukemias: Shikonin, found in Zicao (also known as purple gromwell), suppresses B-Cell and myeloid leukemias via up regulation of the tumor suppressor IRF4, 20/December/2016 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say Noble laureate in Physiology/Medicine (1975) Prof. David Baltimore, from California Institute of Technology, California, USA, had reported in the July 8, 2014 issue of the Journal “Blood” that: “Dual mechanisms by which MiR-125b represses IRF4 to…

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Anti-telomerase cancer therapy: MiR-204 suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) and inhibits cancer progression via down-regulation of it target gene, 16/December/2016, 9.57 pm
Anti-telomerase cancer therapy: MiR-204 suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) and inhibits cancer progression via down-regulation of it target gene, 16/December/2016, 9.57 pm 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say:   The 1989 Nobel prize winner in Chemistry, Prof. Thomas R. Cech from the BioFrontiers Institute, USA has published a research paper in the 13 December 2012 issue of the Nature journal (492(7428):285-9; and I.F: >42) stating that “The TEL patch of telomere protein TPP1…

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Molecular therapy for Bone disorders: ASPP2 (Apoptosis-stimulating protein of Tp53-2) inhibits the expression of Tgif2 and suppresses osteoporosis and bone metastasis via up-regulation of its target gene, 20/December/2016, 9.49 pm
Molecular therapy for Bone disorders: ASPP2 (Apoptosis-stimulating protein of Tp53-2) inhibits the expression of Tgif2 and suppresses osteoporosis and bone metastasis via up-regulation of its target gene, 20/December/2016, 9.49 pm 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say:  A study from the Department of Pharmacology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA has reported that “miR-34a blocks osteoporosis and bone metastasis by inhibiting osteoclastogenesis…

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