Ideas

Therapeutic insights into “awakening the sleeping/cancer-protecting angels” in mutant p53-expressing human tumors: MiR-411 increases the expression of tumor suppressor p53 homologue TA-p73/p63, PTEN, TPM1, TIMP3, BTG2, PDCD4, SPRY1/2 and CCM1/KRIT1 and induces regression of p53-mutated human tumors via down regulation of its target gene, 14/December/2016, 9.28 pm
Therapeutic insights into “awakening the sleeping/cancer-protecting angels” in mutant p53-expressing human tumors: MiR-411 increases the expression of tumor suppressor p53 homologue TA-p73/p63, PTEN, TPM1, TIMP3, BTG2, PDCD4, SPRY1/2 and CCM1/KRIT1 and induces regression of p53-mutated human tumors via down regulation of its target gene, 14/December/2016, 9.28 pm 150 150 Dr Boomi's Genom-2-Discovery Center

From Significance of the study to Public health relevance: Given that: (1) Cancer suppressor p53 is mutated in more than 50% of human cancers of different tissue origin; (2) p53…

read more

Natural product-derived antiviral therapy against chikungunya (CHIKV) and Zika (ZIKV) viruses. Eriocitrin, isolated from lemons, decreases spermidine/spermine N1-acetyltransferase (SAT) expression, depletes spermidine and Spermine levels, and restricts Chikungunya and Zika viruses replication via up regulation of its target gene, 14/December/2015, 7.21 pm
Natural product-derived antiviral therapy against chikungunya (CHIKV) and Zika (ZIKV) viruses. Eriocitrin, isolated from lemons, decreases spermidine/spermine N1-acetyltransferase (SAT) expression, depletes spermidine and Spermine levels, and restricts Chikungunya and Zika viruses replication via up regulation of its target gene, 14/December/2015, 7.21 pm 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Viral Populations and Pathogenesis Unit, Institut Pasteur, CNRS UMR 3569, 25–28 rue du Dr. Roux, 75724 Paris Cedex 15, France shows that…

read more

Mineral-rich water therapy for Myocardial Infarction and Diabetic Nephropathy: Mineral-rich water inhibits DNA damage responses, decreases oxidative stress, inhibits advanced glycation end products, increases telomerase expression, inhibits telomere shortening, promotes cardiomyocyte survival after myocardial infarction and prolongs mammalian life span via up-regulation of PNUTS, 14/December/2016, 13.36 pm
Mineral-rich water therapy for Myocardial Infarction and Diabetic Nephropathy: Mineral-rich water inhibits DNA damage responses, decreases oxidative stress, inhibits advanced glycation end products, increases telomerase expression, inhibits telomere shortening, promotes cardiomyocyte survival after myocardial infarction and prolongs mammalian life span via up-regulation of PNUTS, 14/December/2016, 13.36 pm 150 150 Dr Boomi's Genom-2-Discovery Center

What they say:  A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published in the 7 March  2013 issue of Nature  by Prof Dimmler, Boon, and others. What we…

read more

Natural product Immune enhancement therapy: Fisetin, isolated from Strawberry, blueberries, mangoes, apples, persimmon, kiwi, onions, grapes and cucumber among others, increases SOX2 expression and promotes innate immunity against bacterial infection via down-regulation of its target gene, 14/December/2016, 8.57 am
Natural product Immune enhancement therapy: Fisetin, isolated from Strawberry, blueberries, mangoes, apples, persimmon, kiwi, onions, grapes and cucumber among others, increases SOX2 expression and promotes innate immunity against bacterial infection via down-regulation of its target gene, 14/December/2016, 8.57 am 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say:  A recent study from the Institute of Biophysics, Chinese Academy of Sciences, Beijing, China shows that “Sox2 functions as a sequence-specific DNA sensor in neutrophils to initiate innate immunity…

read more

Therapeutic insights into “awakening the sleeping/cancer-protecting angels” in mutant p53-expressing human tumors: Kuwanon V, one of the constituents of Mulberry, increases the expression of tumor suppressor p53 homologue TA-p73/p63, PTEN, TPM1, TIMP3, BTG2, PDCD4, SPRY1/2 and CCM1/KRIT1 and induces regression of p53-mutated human tumors via down regulation of its target gene, 13/December/2016, 11.35 pm
Therapeutic insights into “awakening the sleeping/cancer-protecting angels” in mutant p53-expressing human tumors: Kuwanon V, one of the constituents of Mulberry, increases the expression of tumor suppressor p53 homologue TA-p73/p63, PTEN, TPM1, TIMP3, BTG2, PDCD4, SPRY1/2 and CCM1/KRIT1 and induces regression of p53-mutated human tumors via down regulation of its target gene, 13/December/2016, 11.35 pm 150 150 Dr Boomi's Genom-2-Discovery Center

From Significance of the study to Public health relevance: Given that: (1) Cancer suppressor p53 is mutated in more than 50% of human cancers of different tissue origin; (2) p53…

read more

Natural product-derived Life-extension therapy: Cinnamaldehyde, one of the constituents of Cinnamon, inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span, 13/December/2016, 11.16 pm
Natural product-derived Life-extension therapy: Cinnamaldehyde, one of the constituents of Cinnamon, inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span, 13/December/2016, 11.16 pm 150 150 Dr Boomi's Genom-2-Discovery Center

What they say? A recent study from the Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK shows that “Ribosomal protein S6 kinase…

read more
Start Typing