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Ideas

March 18, 2017

Natural product-derived therapy for glucose homeostasis and TIIDM: Scopoletin, isolated from Scopolia Japonica, inhibits Amysin expression, increases insulin secretion, and decreases the risk of hyperglycemia via down regulation of its target gene Sox4, 18/March/2017, 8.54 am

Introduction: What they say Nobel laureate in Physiology/Medicine (1975) Prof. David Baltimore and his research team, from California Institute of Technology, California, USA, had reported in […]
March 18, 2017

Natural product-derived therapy for Myocardial Infarction: Calycosin, isolated from Astragalus Membranaceuss, inhibits DNA damage responses, induces telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction via up regulation of PNUTS, 18/March/2017, 7.39 pm

What they say:  A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published in the 7 March  2013 issue of Nature  by Prof Dimmler, […]
March 16, 2017

Natural product-derived anti-metastatic therapy for Notch1-overexpressing Human cancers: Luteolin, one of the main components of Salvia tomentosa, Perilla, and Parsley among others, inhibits the expression of Notch1, and adhesion molecule VCAM1, suppresses neutrophil infiltration and tumor cell adhesion to endothelium, and prevents Notch1-driven metastasis via up regulation of its target gene, 16/March/2017, 11.41 pm

Introduction: What they say: A study from the Vascular Signaling and Cancer, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany; Vascular Biology, CBTM, Medical Faculty Mannheim, […]
March 16, 2017

Molecular therapy for Regenerating the lost pancreatic β-cells in Diabetic patients: TCTP increases the expression of IGF1R, INSR, and IRS2, and promotes an insulin-sensitized state via up-regulation of its target gene, 16/March/2017, 3.25 pm

Introduction: What they say:  A study from the Stem Cell Transplantation Program, Division of Pediatric Hematology/Oncology, Boston Children’s Hospital and Dana-Farber Cancer Institute, Boston, Massachusetts, USA shows that “The […]
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