Ideas

August 25, 2017

Published by admin_auro at August 25, 2017

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Cancer
Ideas

Natural product-derived therapy for EVI-1-Overexpressing Acute Myeloid Leukemia: Dihydroartemisinin (DHA), isolated from Artemesia Annua L, decreases the expression of MECOM/EVI-1 and its down target genes, including CKMT-1, alters Arginine-creatine metabolism, inhibits mitochondrial respiration, depletes ATP levels, and promotes regression of EVI-1-overexpressing AML via up regulation of its target gene, 26/August/2017, 12.56 pm

Introduction: What they say: A study from the Koch Institute for Integrative Cancer Research at Massachusetts Institute of Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA; […]

August 25, 2017

Published by admin_auro at August 25, 2017

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Natural product-derived therapy for tuberculosis: β-Cryptoxanthin, isolated from Paprika, Buah Merah, Papaya, Satsuma Mandarin and among others, inhibits inflammatory gene expression downstream of RelA/p65, inhibits TB pathogenesis, increases the efficacy of anti-TB drug, and promotes M. tuberculosis clearance via up regulation of its target gene, 25/August/2017, 11.59 pm

Introduction: What they say: A study from the Singapore Immunology Network, Agency for Science, Technology and Research, Singapore; and Lee Kong Chian School of Medicine, Nanyang […]

August 25, 2017

Published by admin_auro at August 25, 2017

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Natural product-derived antiviral therapy for HIV virus: Ivermectin (Brand name: Heartguard/Mectizen/Stromectol) increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production via up regulation of its target gene, 25/August/2017, 11.46 pm

Introduction: What they say A study from the Department of Biochemistry and Molecular Biophysics and Department of Microbiology and Immunology, Howard Hughes Medical Institute, Columbia University, […]

August 25, 2017

Published by admin_auro at August 25, 2017

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Natural product-derived therapy for heart regeneration and repair: β-Cryptoxanthin, isolated from Satsuma Mandarin, Buah Merah, Papaya, Paparika and among others, increases Agrin expression, activates Yap and ERK-mediated signaling, replaces scar tissue with functional cardiomyocytes, and promotes cardiomyocyte regeneration and repair after myocardial infarction, via up regulation of its target gene, 25/August/2017, 7.53 am

Introduction: What they say: A recent study from Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 76100, Israel; Department of Biomedical Engineering, Duke University, […]