Ideas

Small molecule-based therapy for increased exercise tolerance and stamina: Apo-10′-lycopenoic acid increases the expression of bidirectional mitochondrial matrix enzyme carnitine acetyltransferase, increases carnitine levels in muscles, and promotes exercise endurance/tolerance via down regulation of its target gene, 31/August/2015, 10.43 pm
Small molecule-based therapy for increased exercise tolerance and stamina: Apo-10′-lycopenoic acid increases the expression of bidirectional mitochondrial matrix enzyme carnitine acetyltransferase, increases carnitine levels in muscles, and promotes exercise endurance/tolerance via down regulation of its target gene, 31/August/2015, 10.43 pm 150 150 Dr Boomi's Genom-2-Discovery Center

A recent study from the Department of Pharmacology and Cancer Biology, Duke University, Durham, NC 27704, USA; Sarah W. Stedman Nutrition and Metabolism Center and Duke Molecular Physiology Institute, Duke University,…

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MiRNA-based therapy for Idiopathic pulmonary fibrosis: Apoptosis-stimulating protein of p53 (ASPP-1) increases TRF1 expression and ameliorates pulmonary fibrosis via up regulation of its target gene, 31/August/2015, 10.33 pm
MiRNA-based therapy for Idiopathic pulmonary fibrosis: Apoptosis-stimulating protein of p53 (ASPP-1) increases TRF1 expression and ameliorates pulmonary fibrosis via up regulation of its target gene, 31/August/2015, 10.33 pm 150 150 Dr Boomi's Genom-2-Discovery Center

A study from the Spanish National Cancer Centre, Melchor Fernández Almagro 3, Madrid, Spain“ shows that: “Mice with Pulmonary Fibrosis Driven by Telomere Dysfunction.” This study was published in the 14 July 2015 issue of the journal “Cell Reports”…

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Regenerative stem cell therapy for Baldness: Taurine, an amino acid, inhibits anagen-to-catagen transition, promotes Keratinocyte Progenitor Cell Expansion and inhibits follicle involution via down regulation of its target gene, 21/June/2015, 11.13 pm
Regenerative stem cell therapy for Baldness: Taurine, an amino acid, inhibits anagen-to-catagen transition, promotes Keratinocyte Progenitor Cell Expansion and inhibits follicle involution via down regulation of its target gene, 21/June/2015, 11.13 pm 150 150 Dr Boomi's Genom-2-Discovery Center

Significance: I have published earlier stating that Taurine may function as a longevity-promoting agent. This study suggests, for the first time, that Taurine, by suppressing the expression of its target gene, it may: (1)…

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Anti-metastasis therapy: MiRNA-3686 suppresses the expression of matrix metalloproteinase (MMP)-2 and MMP-9 via down regulation of its target gene, 21/June/2015, 10.53 am
Anti-metastasis therapy: MiRNA-3686 suppresses the expression of matrix metalloproteinase (MMP)-2 and MMP-9 via down regulation of its target gene, 21/June/2015, 10.53 am 150 150 Dr Boomi's Genom-2-Discovery Center

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan, L., Anti-metastasis therapy: MiRNA-3686 suppresses the expression of matrix metalloproteinase (MMP)-2 and MMP-9 via down regulation of its target gene,…

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Immuno therapy for Cancer: (IFN)-α increases the expression of tumor suppressor PTEN via down regulation of its target gene, 21/June/2015, 9.51 pm
Immuno therapy for Cancer: (IFN)-α increases the expression of tumor suppressor PTEN via down regulation of its target gene, 21/June/2015, 9.51 pm 150 150 Dr Boomi's Genom-2-Discovery Center

Significance: Tumor suppressor PTEN is the second most mutated gene in human cancer.  This study suggests, for the first time, that (IFN)-α, by suppressing the expression of its target gene, it may increase the expression…

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Immune enhancement therapy: Urothelial carcinoma-associated 1 (UCA1) increases SOX2 expression and promotes innate immunity against bacterial infection via down regulation of its target gene, 20/June/2015, 8.47 am
Immune enhancement therapy: Urothelial carcinoma-associated 1 (UCA1) increases SOX2 expression and promotes innate immunity against bacterial infection via down regulation of its target gene, 20/June/2015, 8.47 am 150 150 Dr Boomi's Genom-2-Discovery Center

A recent study from the Institute of Biophysics, Chinese Academy of Sciences, Beijing, China shows that “Sox2 functions as a sequence-specific DNA sensor in neutrophils to initiate innate immunity against microbial infection.” This study…

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