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January 13, 2017
Published by admin_auro at January 13, 2017
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Anti-telomerase cancer therapy: Javamide-II suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) and inhibits cancer progression via down-regulation of it target gene, 13/January/2017, 6.40 am

Introduction: What they say:   The 1989 Nobel prize winner in Chemistry, Prof. Thomas R. Cech from the BioFrontiers Institute, USA has published a research paper in the 13 December 2012 issue of the Nature journal (492(7428):285-9; and I.F: >42) stating that “The TEL […]
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January 12, 2017
Published by admin_auro at January 12, 2017
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Natural product-derived Immune enhancement therapy: Areca Nut extract/Arecoline increases SOX2 expression and promotes innate immunity against bacterial infection via down-regulation of its target gene, 12/January/2017, 10.07 pm

Introduction: What they say:   A recent study from the Institute of Biophysics, Chinese Academy of Sciences, Beijing, China shows that “Sox2 functions as a sequence-specific DNA sensor in […]
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January 12, 2017
Published by admin_auro at January 12, 2017
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Natural product-derived PD-1 pathway blockade for Human cancer therapy: Sauchinone, an antioxidant lignan found in Saururus chinensis, decreases the activity of Glycogen synthase kinase-3β, increases transcription factor T-bet expression, decreases the abundance of co-inhibitory receptor PD-1 on the cell surface of Cytotoxic-T-cells, increases cytotoxic T lymphocyte function and augments anti-tumor activity, via up-regulation of its target gene, 12/December/2016, 9.35 am

Introduction:What they say:  A recent study from Cell Signalling Section, Division of Immunology, Department of Pathology, Tennis Court Road, University of Cambridge, Cambridge CB2 1QP, UK […]
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January 12, 2017
Published by admin_auro at January 12, 2017
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Natural product-derived therapy for Metastatic human tumors: Schisandrin B, one of the main components of Schisandra chinensis, decreases the expression of c-Src protein, inhibits the expression of a number of enzymes in glycolytic cycle, and suppresses proliferation, migration, invasion, tumorigenesis and metastasis via up regulation of its target gene, 12/January/2017, 7.05 am

Introduction: What they say: A study from the State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen […]
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