Ideas

June 18, 2017

Published by admin_auro at June 18, 2017

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Ideas
Pain

The PD-1 pathway activation for Pain therapy: Ethyl Pyruvate (EP) increases the expression of PD-L1, attenuates acutes and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability via up-regulation of its target gene, 18/June/2017, 11.30 pm

Introduction:What they say: A recent study from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain […]

June 17, 2017

Published by admin_auro at June 17, 2017

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Cancer
Ideas

Natural product therapy for KRAS/LKB1-mutant lung cancer: Luteolin, isolated from clover blossom, and Salvia tomentosa, increases the levels of tumor suppressor proteins, inhibits the expression of urea cycle enzyme carbamoyl phosphate synthetase-1 (CSP1), decreases pyrimidine pools, stalls DNA synthesis, and inhibits the progression of KRAS/LKB1-mutated lung cancers via up regulation of its target gene, 18/June/2017, 12.50 am

Introduction: What they say A study from the Children’s Medical Center Research Institute, UT Southwestern Medical Center, Dallas, Texas 75390, USA; Department of Pediatrics, UT Southwestern […]

June 17, 2017

Published by admin_auro at June 17, 2017

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Cancer
Ideas

Natural product-derived therapy for Chronic Myeloid leukaemia (CML): Cucurbitacin D, found in watermelon, decreases the expression of Musashi2, inhibits cytosolic aminotransferase BCAT1 expression, decreases the intracellular production of BCAAs (Branched-chain amino acids), increases the expression of tumor suppressor genes, promotes differentiation of CML cells, and inhibits cancer progression in Myeloid leukemia via up-regulation of its target gene, 18/June/2017, 12.28 am

Introduction: What they say: A study from the Department of Biochemistry-Molecular Biology, Franklin College of Arts and Sciences, The University of Georgia, Athens, Georgia 30602, USA; […]

June 17, 2017

Published by admin_auro at June 17, 2017

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Amino acid-based therapy for heart regeneration and repair: Taurine , found in Cottage cheese, Granola and among others, increases Agrin expression, activates Yap and ERK-mediated signaling, replaces scar tissue with functional cardiomyocytes, and promotes cardiomyocyte regeneration and repair after myocardial infarction, via up regulation of its target gene, 18/June/2017, 12.13 am

Introduction: What they say: A recent study from Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 76100, Israel; Department of Biomedical Engineering, Duke University, […]