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April 5, 2017
Published by admin_auro at April 5, 2017
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Natural product-based therapy for ageing-associated diseases: 2,4,5-trihydroxybenzaldehyde (TDB), found in Geum japonicum and Polygonum cuspidatum (PC), also known as Japanese knotweed, increases NMN/NAD levels, decreases interaction of DBC1 with PARP1, increases PARP1 activity, promotes DNA repair, augments tolerance against radiation, cancer and aging via down regulation of its target gene, 5/April/2017, 7.41 pm

Introduction: What they say A study from Department of Genetics, Paul F. Glenn Center for the Biology of Aging, Harvard Medical School, Boston, MA, USA; and […]
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April 5, 2017
Published by admin_auro at April 5, 2017
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Natural product-derived antiviral therapy against Neuroinvasive West Nile virus: Naringenin, a class of flavonoid found in Citrus fruits, increases the expression of RIPK3, promotes chemokines production, inhibits neuroinflammation, and restricts neuroinvasive West Nile virus production and pathogenesis in neurons via up regulation of its target gene, 5/April/2017, 2.13 pm

Introduction: What they say A study from the Department of Immunology, University of Washington, Seattle, WA 98109, USA; Center for Innate Immunity and Immune Disease, University […]
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April 5, 2017
Published by admin_auro at April 5, 2017
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Natural product-derived antiviral therapy against chikungunya (CHIKV) and Zika (ZIKV) viruses: Linalool, found in coriander, sweet orange (Citrus sinensis), tomato, oils of rose, neroli, lavender, laurel and sweet basil (Ocimum basilicum) among others, decreases spermidine/spermine N1-acetyltransferase (SAT) expression, depletes spermidine and Spermine levels, and restricts Chikungunya and Zika viruses replication via up regulation of its target gene, 5/April/2017, 1.54 pm

Introduction: What they say A study from the Viral Populations and Pathogenesis Unit, Institut Pasteur, CNRS UMR 3569, 25–28 rue du Dr. Roux, 75724 Paris Cedex […]
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April 5, 2017
Published by admin_auro at April 5, 2017
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Small molecule based-therapy for Regenerating the lost pancreatic β-cells in Diabetic patients: Trichostatin A, a histone deacetylase inhibitor, increases the expression of IGF1R, INSR, and IRS2, and promotes an insulin-sensitized state via up-regulation of its target, 5/April/2017, 6.21 am

Introduction: What they say:  A study from the Stem Cell Transplantation Program, Division of Pediatric Hematology/Oncology, Boston Children’s Hospital and Dana-Farber Cancer Institute, Boston, Massachusetts, USA shows that “The […]
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